Results 111 to 120 of about 23,147 (265)

Core-Sheath Nanofibers From a Modified Coaxial Electrospinning for Transdermal Delivery of Finasteride. [PDF]

ChemistryOpen
Sun L, Zhao Y, Caomeng X, Yu DG, Liu P.
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Mechanistic Modelling of Transdermal Delivery Dependence on Drug Properties. [PDF]

Pharm Res
Benbrook N, Zhan W.
europepmc   +1 more source

Transdermal Delivery of Analgesics [PDF]

Therapeutic Delivery, 2011
openaire   +2 more sources

A narrow bandgap Schottky heterojunction Fe2N/CeO2 microneedle triggering sonodynamic reactive oxygen species storm for drug‐resistance‐free skin fungal infection

BMEMat, EarlyView.
Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang, Jiayi Yang, Ning Tang, Youbin Zheng, Yichao Hou, Chutong Liu, Lihao Guo, Yingying Liao, Gandong Zhou, Weiwei Wu, Xin Du, Shuxiang Xu, Jie Yin, Miaomiao Yuan   +13 more
wiley   +1 more source

Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems. [PDF]

Pharmaceutics
Li K, Yan B, Cao Z, Lu R, Wu G, Hai Y.
europepmc   +1 more source

Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Leah M. Gober, Michael A. Stellon, Matt A. Culver, Amy Frenkel, Dana Irrer, Colleen M. Witzenburg, Alejandro Roldán‐Alzate, Luke Lamers   +7 more
wiley   +1 more source

Transdermal Delivery of Chinese Medicinal Formula Mitigates Pediatric Constipation by Modulating Intestinal Endocrine and Metabolic Homeostasis. [PDF]

Biomater Res
Song F, Ren Y, Zhu M, Liu Y, Wei S, Li H, Peng L.   +6 more
europepmc   +1 more source

Same‐Day Discharge After Transcatheter Aortic Valve Implantation: Who, When, and How?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The burden of severe aortic stenosis requiring treatment is growing due to ageing populations. This places increased demands on health resources due to the growing number of transcatheter aortic valve implantation (TAVI) procedures and hospital bed occupancy.
Hilal Khan, Debbie Stewart, Sarah Lamb, Rajiv Das, Richard Edwards, Timothy Cartlidge, Mohammad Alkhalil, Azfar Zaman, Mohamed Farag   +8 more
wiley   +1 more source