Results 91 to 100 of about 23,063 (265)

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

Anti‐inflammatory and osteogenic effects of transcutaneous electrical nerve stimulation in knee osteoarthritis rats via the regulation of the intestinal microbiota

Animal Models and Experimental Medicine, EarlyView.
Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun, Tong Ma, Ran Chen, Lan Shen, Xun Tang, Zhiqiang Shen, Hongbin Zhao   +6 more
wiley   +1 more source

Microneedle‐Based Biofuel Cell with MXene/CNT Hybrid Bioanode: Fundamental and Biomedical Application

Advanced Science
Biofuel cells show emerging potential as energy‐supply platform by harvesting bioenergy from human biofluids for next‐generation self‐powered transdermal drug delivery systems.
Shoujie Guan, Jingxi Wang, Yang Yang, Xun Zhu, Jianping Zhou, Dingding Ye, Rong Chen, Qinlin Fan, Qiang Liao   +8 more
doaj   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source

Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana, Thambaramala V. Gamage, Tanoj K. Singh, Shuaifei Zhao, Amy Logan, Lingxue Kong   +5 more
wiley   +1 more source

Breaking boundaries: the advancements in transdermal delivery of antibiotics

Drug Delivery
Transdermal drug delivery systems (TDDS) for antibiotics have seen significant advances in recent years that aimed to improve the efficacy and safety of these drugs.
Ahlam Zaid Alkilani, Rania Hamed, Batool Musleh, Zaina Sharaire   +3 more
doaj   +1 more source

Knotless Suture Staple Remplissage for Hill‐Sachs Lesions in the Beach Chair Position

Arthroscopy Techniques, EarlyView.
Abstract The addition of remplissage to arthroscopic Bankart repair in the presence of a Hill‐Sachs lesion can help decrease recurrence of anterior shoulder instability. The remplissage procedure often involves passage of suture from anchors in the Hill‐Sachs lesion to the extra‐articular side of the shoulder capsule followed by knot tying.
Joseph M. Sliepka, Benjamin Lurie, Alan L. Zhang   +2 more
wiley   +1 more source

Arthroscopic Repair of Radial Meniscal Tear Using Fibrin Clot Augmentation and “Hashtag” Style Inside‐Out Technique

Arthroscopy Techniques, EarlyView.
Abstract Significant meniscal injuries lead to pain and possible early osteoarthritis development. Fibrin clot augmentation represents an effective, cost‐efficient method for improving healing rates in poorly vascularized meniscal tears. This arthroscopic technique shows fibrin clot augmentation combined with horizontal and vertical mattress sutures in
Siddharth Padmanabhan, Helena Franco, Peter Myers, Francois Tudor   +3 more
wiley   +1 more source

The Tendon‐to‐Bone Seam: A Transtendinous Approach to Rotator Cuff Repair

Arthroscopy Techniques, EarlyView.
Abstract This technique article describes the tendon‐to‐bone seam technique, a knotless, transtendinous approach to arthroscopic rotator cuff repair. The technique employs a single‐use deployment device preloaded with multiple PEEK anchors interconnected with a single polyethylene #2 suture, enabling the surgeon to create a continuous “seam” of ...
James Tyler Frix, Ryan Serbin, Howard W. Harris, Marc R. Labbe, Patrick M. Connor   +4 more
wiley   +1 more source