Results 91 to 100 of about 23,147 (265)

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana, Thambaramala V. Gamage, Tanoj K. Singh, Shuaifei Zhao, Amy Logan, Lingxue Kong   +5 more
wiley   +1 more source

Advances in Transdermal Drug Delivery Systems and Clinical Applications in Inflammatory Skin Diseases

Pharmaceutics
Inflammatory skin diseases are highly prevalent conditions characterized by complex immune responses that result in skin tissue damage and pain, significantly impacting patients’ physical health.
Sizhuo Liu, Tinghan Deng, Hongbin Cheng, Jun Lu, Jingping Wu   +4 more
doaj   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, EarlyView.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Arthroscopic Repair of Radial Meniscal Tear Using Fibrin Clot Augmentation and “Hashtag” Style Inside‐Out Technique

Arthroscopy Techniques, EarlyView.
Abstract Significant meniscal injuries lead to pain and possible early osteoarthritis development. Fibrin clot augmentation represents an effective, cost‐efficient method for improving healing rates in poorly vascularized meniscal tears. This arthroscopic technique shows fibrin clot augmentation combined with horizontal and vertical mattress sutures in
Siddharth Padmanabhan, Helena Franco, Peter Myers, Francois Tudor   +3 more
wiley   +1 more source

A two-stage transdermal drug delivery system comprising sono-phase-change transfersomes for non-invasive deep dermal delivery

Journal of Nanobiotechnology
Non-invasive deep transdermal drug delivery is required for conditions such as keloids. However, the skin’s stratum corneum barrier is the primary obstacle for transdermal drug delivery methods.
Yi Zhang, Xiong He, Xiang Mao, Yukun Yang, Faqi Li, Xiaofeng Han, Hao Lu, Liang Tang, Yujun Yang, Yan Wang, Yuling Du, Wei Xu, Zhenyu Wang   +12 more
doaj   +1 more source

The Tendon‐to‐Bone Seam: A Transtendinous Approach to Rotator Cuff Repair

Arthroscopy Techniques, EarlyView.
Abstract This technique article describes the tendon‐to‐bone seam technique, a knotless, transtendinous approach to arthroscopic rotator cuff repair. The technique employs a single‐use deployment device preloaded with multiple PEEK anchors interconnected with a single polyethylene #2 suture, enabling the surgeon to create a continuous “seam” of ...
James Tyler Frix, Ryan Serbin, Howard W. Harris, Marc R. Labbe, Patrick M. Connor   +4 more
wiley   +1 more source

Cytotoxicity study of transdermal desloratadine delivery system on murine melanoma and human dermal fibroblast cell cultures

Research Results in Pharmacology
Introduction: Transdermal delivery of antihistamines is one of the ways to treat and prevent allergic conditions, reducing the adverse effects associated with oral administration. Materials and Methods: We evaluated the cytotoxicity of the transdermal
Ekaterina P. Brodovskaya, Aminah M. Al-Hajj Ayub, Dmitry O. Semikov, Valentine P. Ageev, Andrey V. Zaborovskiy, Larisa A. Tararina, Dina V. Yunina, Sergey A. Litvinov, Izabella M. Dadaeva, Natalia V. Kheladze, Dmitriy N. Andreev, Elena G. Lobanova, Nikolay A. Pyataev   +12 more
doaj   +1 more source

Arthroscopic High‐in‐the‐Groove Biceps Tenodesis: Loop‐and‐Tack Technique

Arthroscopy Techniques, EarlyView.
Abstract Arthroscopic biceps tenodesis is an effective treatment for patients with long head of the biceps tendon pathology. This technical note details a high‐in‐the‐groove arthroscopic technique utilizing loop‐and‐tack fixation through a single cannula.
Marc Nicholes, Micah Ngatuvai, Nata Parnes, John P. Scanaliato   +3 more
wiley   +1 more source

Promotion of the transdermal delivery of protein drugs by N-trimethyl chitosan nanoparticles combined with polypropylene electret

International Journal of Nanomedicine, 2016
Ye Tu,1,2,* Xinxia Wang,3,* Ying Lu,2,* He Zhang,2 Yuan Yu,2 Yan Chen,2 Junjie Liu,2 Zhiguo Sun,2 Lili Cui,4 Jing Gao,2 Yanqiang Zhong2 1Department of Medical Affairs, East Hospital, Tongji University School of Medicine, 2Department of Pharmaceutical ...
Tu Y, Wang X, Lu Y, Zhang H, Yu Y, Chen Y, Liu J, Sun Z, Cui L, Gao J, Zhong Y   +10 more
doaj