Results 101 to 110 of about 23,147 (265)

Arthroscopic Treatment of Schatzker Type III Tibial Plateau Fractures Using a Combination of Bioabsorbable Interference Screws and Cannulated Screws

open access: yesArthroscopy Techniques, EarlyView.
Abstract Schatzker type III tibial plateau fractures, characterized by a pure depression of the lateral articular surface, predominantly affect osteoporotic, middle‐aged, and elderly patients. Successful management requires anatomical reduction and stable fixation to minimize complications like post‐traumatic arthritis.
Renbang Huang   +3 more
wiley   +1 more source

The “Tie Stitch”: An Arthroscopic Stich for Long Head of Biceps Tenodesis Associated With Rotator Cuff Repair or as a Superior Capsule Reconstruction. Surgical Step‐by‐Step Technique

open access: yesArthroscopy Techniques, EarlyView.
Abstract Long head of biceps (LHB) tenodesis is a common procedure. Historically, it has been recommended in the setting of rotator cuff reconstruction in young and active patients when the LHB is degenerated or severely inflamed to reduce postoperative pain.
Simone Cerciello   +5 more
wiley   +1 more source

Combined Arthroscopic Medial Meniscal Root Repair and Centralization Using All‐Suture Anchors Without a Posteromedial Portal

open access: yesArthroscopy Techniques, EarlyView.
Abstract Medial meniscus posterior root tears frequently result in meniscal extrusion and disruption of normal tibiofemoral contact mechanics. Several techniques, including transtibial pullout and anchor‐based repair methods, are used for root repair and meniscus centralization.
Coşkun Genç   +5 more
wiley   +1 more source

Arthroscopic All‐Inside/All‐Suture Repair of Complete Radial Tear of the Lateral Meniscus Using a Percutaneous Single‐Needle Technique

open access: yesArthroscopy Techniques, EarlyView.
Abstract Radial tears of the lateral meniscus have limited healing potential and unfavorable biomechanics, and current suture constructs that use capsular rip‐stop stitches may increase meniscal extrusion and constrain native motion. This technical note describes an all‐inside, crossed, meniscus‐based repair for complete or near‐complete radial tears ...
Diego Sánchez Cruz   +3 more
wiley   +1 more source

Double Transverse Mini‐Incision Repair for Proximal Achilles Tendon Tears

open access: yesArthroscopy Techniques, EarlyView.
Abstract Recent literature showing equivalent outcomes for surgical and nonoperative management of Achilles tendon ruptures emphasizes the importance of proper indications for surgical repair. Various techniques for tendon repair via reapproximation of the torn ends have been described, such as open, mini‐open, and minimally invasive, each with their ...
Taylor Stauffer   +4 more
wiley   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano   +6 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) microsphere loaded dissolving microneedles for sustained and coordinated transdermal delivery of desogestrel and ethinyl estradiol

open access: yesBulletin of the Korean Chemical Society, EarlyView.
PLGA‐based sustained‐release microneedles were developed for the delivery of desogestrel and ethinyl estradiol. The system enabled coordinated release of both drugs, suggesting its potential to improve dosing convenience as a long‐acting contraceptive platform.
Young‐Jin Kim   +5 more
wiley   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

open access: yesBMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang   +5 more
wiley   +1 more source

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