Results 141 to 150 of about 3,038,700 (252)

Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

BMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao, Yujie Luo, Chuanda Zhu, Yanwei Hu   +3 more
wiley   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo

International Journal of Nanomedicine, 2011
Ji-Hui Zhao, Li Ji, Hui Wang, Zhi-Qiang Chen, Yong-Tai Zhang, Ying Liu, Nian-Ping FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaObjective: To deliver 2,3,5,6-tetramethylpyrazine ...
Zhao JH, Ji L, Wang H, Chen ZQ, Zhang YT, Liu Y, Feng NP   +6 more
doaj  

Intrathecal Drug Delivery

Intrathecal drug delivery systems are a means to provide direct administration of medications into the cerebrospinal fluid (CSF). Bypassing the blood-brain barrier allows a significantly lower dose of medication to be administered to attain analgesia ...
Chandran, S
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Tannic acid–metal biomaterials for skin repair: Principles, immune microenvironment modulation, and translational perspectives

BMEMat, EarlyView.
Tannic acid–metal materials are emerging as versatile wound biomaterials, but their value depends on more than multifunctionality. This review maps how tannic acid alone, free metal ions, and coordinated TA–metal systems differ in design logic, immune‐microenvironment effects, and translational potential, offering a practical framework for choosing ...
Shahid Mahmood, Nan Li, Dandan Yang, Chunhui Sun, Yu Wang, Dongzhou Wang, Congcong Zhang   +6 more
wiley   +1 more source

A high throughput strategy for traditional Chinese medicine active compound screening based on Raman spectroscopy

Journal of Pharmaceutical Analysis
Mengyin Tian, Xiaobo Ma, Yuandong Li, Hengchang Zang, Lian Li   +4 more
doaj   +1 more source

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani, Gonzalo García‐Martí, Andrés Provencio‐Regidor, Irene Serrano‐García, Adrián Jerónimo‐Baza, Alejandro Travieso, Gabriela Tirado‐Conte, Fernando Macaya‐Ten, Hernán Mejía‐Rentería, Pablo Salinas, Luis Nombela‐Franco, Pilar Jiménez‐Quevedo, Nieves Gonzalo, Javier Escaned, Antonio Fernández‐Ortiz, Iván J. Núñez‐Gil   +15 more
wiley   +1 more source

Maximum Allowable Contrast Dose and Risk of Acute Kidney Injury After Coronary Procedures

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Recent studies have questioned whether iodinated contrast is causally related to acute kidney injury (AKI). AIM We pursed a contemporary analysis to determine the impact of contrast dose on AKI following coronary procedures in an era of lower contrast doses and less nephrotoxic agents.
Harshita Gaba, Elise Mesenbring, Christine Chow, Jennifer A. Rymer, Celina M. Yong, Stephen W. Waldo, Jacob A. Doll   +6 more
wiley   +1 more source

Consensus on Transdermal Drug Delivery Technologies

Supplementary Information of International Expert Consensus on Transdermal Drug Delivery Technologies in ...
Tao, Juan
core   +1 more source