Results 151 to 160 of about 20,274 (254)

Mono‐ and Bivalent Poly(iso‐butylene)‐Alanines for Drug‐Delivery of Nimodipine and Triamcinolone Acetonide

Macromolecular Rapid Communications, EarlyView.
Mono‐ and bivalent‐, alanine‐modified poly‐iso‐butylenes, folding into beta‐sheets, were prepared by living carbocationic polymerization and subsequent endgroup modification. These PIB‐conjugates are useful as solid polymers for the drug release of triamcinolone and nimodipine. ABSTRACT Poly‐iso‐butylene (PIB) is a well known biocompatible polymer with
Philipp S. Hilgeroth, Julius F. Butter, Wolfgang H. Binder   +2 more
wiley   +1 more source

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou, John T. Leman, Harper Serringer, Ke Xia, Christopher N. LaFratta, Chaitanya Ullal, Edmund F. Palermo   +6 more
wiley   +1 more source

Transdermal Drug Delivery: An Overview of the Evolving Field. [PDF]

Balkan Med J
Aktürk G, Gündüz Ö.
europepmc   +1 more source

Fabrication of Microneedles by Pulsating In Situ Dried Electrostretching for Transdermal Drug Delivery. [PDF]

Small Methods
Mai NL, Yong Y, Hoang TVA, Vu TH, Vu HD, Doan VC, Cai D, Dinh TX, Dao DV, Dau VT.   +9 more
europepmc   +1 more source

Continuous Subcutaneous Versus Intestinal Levodopa Infusion for Parkinson's Disease: A Real‐World, Monocentric, Observational Study and Critical Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Subcutaneous foslevodopa‐foscarbidopa (SCFF) is a novel, non‐surgical dopaminergic infusion therapy for better controlling motor fluctuations in advanced Parkinson's disease (PD). However, there are scarce real‐world data on efficacy, adverse events and comparisons with other infusion strategies. Objectives Here, we aimed to provide
Johannes Hartig, Lennert Sitzmann, Doreen Hartenstein, Marion Labisch, Chi Wang Ip, Jens Volkmann, Christine Daniels   +6 more
wiley   +1 more source

A Four-Layer Numerical Model for Transdermal Drug Delivery: Parameter Optimization and Experimental Validation Using a Franz Diffusion Cell. [PDF]

Pharmaceutics
Jonsdottir F, Finsen OI, Snorradottir BS, Sigurdsson S.   +3 more
europepmc   +1 more source

Active Electromagnetic Interference Suppression for MRI and Proton Resonance Frequency Shift Thermometry During MRI‐Guided Microwave Ablation

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a software‐based active electromagnetic interference (EMI) suppression (AES) framework on whole‐body multi‐channel MRI systems for reliable MRI and MR thermometry during MRI‐guided microwave ablation (MWA). Methods In addition to primary imaging coils, an unloaded standard body array coil was positioned outside the imaging ...
Qing Dai, Jason Chiang, Shu‐Fu Shih, Wenqi Zhou, David S. K. Lu, Holden H. Wu   +5 more
wiley   +1 more source

Mathematical modelling of hollow microneedle-mediated transdermal drug delivery. [PDF]

Drug Deliv Transl Res
Benbrook N, Zhan W.
europepmc   +1 more source

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is a gene‐targeted therapy for individuals with superoxide dismutase 1 (SOD1) (+) amyotrophic lateral sclerosis (ALS). Prior to U.S. Food and Drug Administration (FDA) approval, tofersen was made available through expanded access protocol.
Alison Wheeler, Kush Mehta, Danica Sanders, Cathy Chin, Hannah Zivalic, Judith Carey, Alexandra McCaffrey, Pravin Pant, Carl Lewenhaupt, Sarah Luppino, Gabriel Jacobs, Shea Golden, Ryan Gifford, Erica Scirocco, Mackenzie Keegan, Munaf Hatem, Taravat Yazdanian, Sanem P. Uysal, Natalie Susco, Shauna Schwartzman, Karen Branch, Kathryn E. Hall, Joanna Barnas, Jenny Lam, Jennifer Hagar, Carol Ann Hannan, Sabrina Paganoni, James D. Berry, Mark Garret, Jennifer Scalia, Suma Babu   +30 more
wiley   +1 more source

Rapid dissolving microneedle patch integrated with benidipine-loaded nanotransfersomes for transdermal drug delivery: optimization, characterizations, and preclinical bioavailability assessment. [PDF]

Drug Deliv Transl Res
Al-Japairai K, Almurisi SH, Alheibshy F, Abdul-Halim N, Mahmood S.   +4 more
europepmc   +1 more source