Results 181 to 190 of about 3,038,700 (252)

Iontophoresis-assisted transdermal drug delivery for the treatment of inflammatory dermatoses: A review. [PDF]

J Pharm Anal
Wang Z, Jiang X, Jiang C, Tao X, Ye J.
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Microneedle-Based Technologies for Long-Acting Transdermal Drug Delivery in Wearable Devices. [PDF]

Sensors (Basel)
Luo J, Dai Y, Cheng X, Wang Z, Zhu Z.
europepmc   +1 more source

Transcutaneous auricular vagus nerve stimulation in drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial with exploratory EEG and MRI response phenotyping

Epilepsia Open, EarlyView.
Abstract Objective Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive neuromodulation strategy for drug‐resistant epilepsy, but clinical response is heterogeneous. We examined whether electroencephalographic (EEG) and structural magnetic resonance imaging (MRI) phenotypes were associated with active‐specific clinical benefit from
Sung Jun Hong, Seok‐Yeol Yang, Eun Kyung Bok, Jung Chul Lee, Yeonggin Kim, Kyousik Min, Young‐Min Shon   +6 more
wiley   +1 more source

Electrospun Polycaprolactone/Carbon Nanotube Membranes for Transdermal Drug Delivery Systems. [PDF]

Polymers (Basel)
Ortiz-Maldonado E, San Martin-Martínez E, Gama-Castañeda NO, Pacheco M, Figueroa-López U, Guevara-Morales A, Juárez E, Ruiz A, Vieyra H.   +8 more
europepmc   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Advances in Transdermal Drug Delivery Systems for Antithrombotic Therapy: A Systematic Review. [PDF]

ACS Pharmacol Transl Sci
Stersi MAD, Nader-Mota GC, Suzuki EY, Cabral LM, Sathler PC, do Carmo FA.   +5 more
europepmc   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source

Azelaic acid-integrated therapeutic deep eutectic systems: overcoming solubility and permeability barriers for enhanced transdermal drug delivery. [PDF]

RSC Adv
Du L, Wang S, Chen H, Liu C, Yang S, Wang Y, Cai B, Yang J, Ding Y.   +8 more
europepmc   +1 more source

The Needle‐Free Frontier: Redefining the Limits of Transdermal Insulin Delivery

Exploration, EarlyView.
Wei and colleagues reported a pH‐responsive, charge‐switchable polyzwitterionic polymer carrier that achieves non‐invasive transdermal insulin delivery without external energy input. The approach leverages adaptive compatibility with the cutaneous microenvironment to shuttle functional macromolecules across intact skin and achieve definitive systemic ...
Junge Chen, Yuxuan Liu, Bozhang Xia, Julien Milon Essola, Xing‐Jie Liang   +4 more
wiley   +1 more source