Results 181 to 190 of about 20,334 (253)

Corrigendum: Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery. [PDF]

J Pharm Pharm Sci
Meng F, Qiao X, Xin C, Ju X, He M.
europepmc   +1 more source

Reconciling Granular Hydrogel Microstructure and Mechanics via a Temporary Thermo‐Responsive and Cell‐Invadable Matrix

Small, EarlyView.
Thermo‐responsive granular hydrogels (TRGHs), composed of microparticles and an interstitial matrix, exhibit thermo‐responsive mechanical properties and allow cell infiltration. This system effectively addresses the conventional compromise between mechanical strength and porosity observed in granular hydrogels.
Jun Kim, Soyeon Kwon, Taimoor H. Qazi
wiley   +1 more source

AI-Driven Innovation in Skin Kinetics for Transdermal Drug Delivery: Overcoming Barriers and Enhancing Precision. [PDF]

Pharmaceutics
Albayati N, Talluri SR, Dholaria N, Michniak-Kohn B.   +3 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Noninvasive Novel Transdermal Drug Delivery System for Deep Drug Permeability. [PDF]

Research (Wash D C)
Han H, Santos HA.
europepmc   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Modified Phospholipid Vesicular Gel for Transdermal Drug Delivery: The Influence of Glycerin and/or Ethanol on Their Lipid Bilayer Fluidity and Penetration Characteristics. [PDF]

Gels
Abdallah MH, Shahien MM, El-Horany HE, Ahmed EH.   +3 more
europepmc   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Atorvastatin loaded glycerosomal patch as an effective transdermal drug delivery: optimization and evaluation. [PDF]

Ther Deliv
Patil P, Rahangdale M, Sawant K.
europepmc   +1 more source

Effect of transcutaneous electrical nerve stimulation on physical activity and pain evaluation in osteoarthritic dogs

Veterinary Record, EarlyView.
Abstract Background Osteoarthritis (OA) causes chronic pain and reduces welfare in dogs. Standard treatments may be inadequate or associated with adverse effects, prompting investigation of alternative therapies. Transcutaneous electrical nerve stimulation (TENS) is a non‐pharmacological pain management method, but evidence for its efficacy in canine ...
Anja Pedersen, Johanna Penell, Emil Olsen, Heli Hyytiäinen, Franck Forterre, Anna Bergh   +5 more
wiley   +1 more source