Results 111 to 120 of about 16,839 (284)
Pharmacokinetic profile of a new matrix-type transdermal delivery system: Diclofenac diethyl ammonium patch [PDF]
, 1999 A transdermal delivery system containing the anti-inflammatory analgesic diclofenac diethyl ammonium in an ethyl hexyl acrylate and vinyl acetate pressure-sensitive adhesive system was developed for percutaneous absorption.
Devi, K., Paranjothy, K.L.K.
core +1 more source
In vitro skin permeation of buprenorphine transdermal patch
Journal of Food and Drug Analysis, 2020 This study was aimed to develop the new transdermal formulation to improve the permeability of buprenorphine. The apparent partition coefficients of buprenorphine were measured using the buffers at pH 1.2 to 10.0 as aqueous phase. The solubility of buprenorphine was 12.97 μg/mL in the 0.1 M phosphate buffer at pH 6.8.
Chang-Liang Liao +5 more
openaire +2 more sources
Advanced Science, EarlyView.Microcapsule‐based intelligent coatings (MICs) have shown great potential in the fields of biomedicine, smart buildings, marine protection, and aerospace. However, they currently face challenges in the integration of coating functions and applications in complex systems.
Yue Zhao +5 more
wiley +1 more source
Topical delivery of hexamidine [PDF]
, 2016 Hexamidine diisethionate (HEX D) has been used for its biocidal actions in topical preparations since the 1950s. Recent data also suggest that it plays a beneficial role in skin homeostasis.
Hadgraft, J +5 more
core +1 more source
Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives
Aggregate, EarlyView.Triterpenoids serve as both exceptional molecular motifs for supramolecular assembly and versatile therapeutic agents, offering broad biological functions to improve health outcomes and enhance treatment efficacy. This review comprehensively summarizes recent advances in triterpenoid‐based supramolecular systems, including their roles as functional ...
Jie Zhong +3 more
wiley +1 more source
A multicenter, open-label, long-term safety and tolerability study of DFN-02, an intranasal spray of sumatriptan 10 mg plus permeation enhancer DDM, for the acute treatment of episodic migraine. [PDF]
, 2017 BackgroundDFN-02 is a novel intranasal spray formulation composed of sumatriptan 10 mg and a permeation-enhancing excipient comprised of 0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside (DDM).
Allenby, Kent +5 more
core +1 more source
Advanced Nanoscale Functionalities for Water and Energy Technologies
Advanced Physics Research, EarlyView.Nanofluidics explores fluid and ion transport under nanoscale confinement, driving advancements in water treatment and energy technologies. With applications in high‐efficiency desalination, osmotic energy generation, and scalable energy storage, it leverages unique material properties and confinement effects to address critical challenges in ...
Zhi Xu +8 more
wiley +1 more source
New patents on topical anesthetics. [PDF]
, 2014 Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano +6 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims There is a potential risk of systemic side‐effects with the use of potent corticosteroids, such as clobetasol propionate (CP). This concern is of particular interest in paediatric patients. The aim of this study was to develop and verify a physiologically based pharmacokinetic (PBPK) model to describe the local and systemic exposure to CP
Janna K. Duong +6 more
wiley +1 more source
Enhanced delivery of hydrophilic peptides in vitro by transdermal microneedle pretreatment
Acta Pharmaceutica Sinica B, 2014 The aims of this study were to investigate the utility of solid microneedle arrays (150 µm in length) in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D2O flux.
Suohui Zhang, Yuqin Qiu, Yunhua Gao
doaj +1 more source