Results 91 to 100 of about 418,457 (205)

In vivo Leukemogenesis Model Using Retrovirus Transduction

Bio-Protocol, 2017
Various genetic alterations such as chromosomal translocation cause leukemia. For examples, gene rearrangements of the mixed-lineage leukemia (MLL) gene generate MLL fusion genes, whose products are potent oncogenic drivers in acute leukemia.
Hiroshi Okuda, Akihiko Yokoyama
doaj   +1 more source

Genetic Analysis of Gibberellin Signal Transduction [PDF]

Plant Physiology, 1996
S. M., Swain, N. E., Olszewski
openaire   +2 more sources

Enhancing Gene Delivery in NB-4 Cells: Overcoming Transduction and Selection Challenges

Cells
Efficient gene transduction and cell viability are critical factors in genetic manipulation for research and therapeutic purposes. In this study, we explored the challenges associated with transducing the NB-4 cell line, a well-established model for ...
Stefano Leto, Sonakshi Gehlot, Bhavwanti Sheth, Stefano Ratti, Lucia Manzoli, Nullin Divecha, Roberta Fiume   +6 more
doaj   +1 more source

Gene delivery to pancreatic exocrine cells in vivo and in vitro

BMC Biotechnology, 2012
Background Effective gene transfer to the pancreas or to pancreatic cells has remained elusive although it is essential for studies of genetic lineage tracing and modulation of gene expression. Different transduction methods and viral vectors were tested
Houbracken Isabelle, Baeyens Luc, Ravassard Philippe, Heimberg Harry, Bouwens Luc   +4 more
doaj   +1 more source

Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells [PDF]

: Quiescent human hematopoietic stem cells (HSC) are ideal targets for gene therapy applications due to their preserved stemness and repopulation capacities; however, they have not been exploited extensively because of their resistance to genetic ...
Unali, Giulia, Benedicenti, Fabrizio, Oo, Adrian, Pais, Giulia, Castiglioni, Ilaria, Spinozzi, Giulio, Kim, Baek, Landau, Nathaniel R, Ferrari, Giuliana, Valeri, Erika, Cuccovillo, Ivan, Abou-Alezz, Monah, Kajaste-Rudnitski, Anna, Behrendt, Rayk, Piras, Francesco, Arévalo, Sergio, Merelli, Ivan, Lidonnici, Maria Rosa, Montini, Eugenio   +18 more
core   +1 more source

AAV-mediated transduction of songbird retina [PDF]

Introduction: Genetic manipulation of murine retinal tissue through ocular administration of adeno-associated viruses (AAVs) has become a standard technique to investigate a multitude of mechanisms underlying retinal physiology. Resultantly, developments
Heyers, Dominik, Koch, Karl-Wilhelm, Dedek, Karin, Satish, Baladev, Borowsky, Lisa, Scharff, Constance, Feederle, Regina, Seth, Pranav Kumar, Haase, Katrin, Mendoza, Ezequiel, Musielak, Isabelle, Mouritsen, Henrik   +11 more
core   +2 more sources

Comparative transcriptome analysis identifies key regulators of nitrogen use efficiency in chrysanthemum

Journal of Integrative Agriculture
Nitrogen (N) is a limiting factor that determines the yield and quality of chrysanthemum. Genetic variation in N use efficiency (NUE) has been reported among chrysanthemum genotypes.
Lijiao Ge, Weihao Miao, Kuolin Duan, Tong Sun, Xinyan Fang, Zhiyong Guan, Jiafu Jiang, Sumei Chen, Weimin Fang, Fadi Chen, Shuang Zhao   +10 more
doaj   +1 more source

Genetic Recombination by Transduction in Salmonella

Cold Spring Harbor Symposia on Quantitative Biology, 1958
M, DEMEREC, I, GOLDMAN, E L, LAHR
openaire   +2 more sources

ApoE gene therapy: an overview and update

, 2005
Atherosclerosis remains the leading cause of death in industrialized societies. Apolipoprotein E (ApoE) is an attractive candidate to treat hypercholesterolemia and coronary heart disease, as it is a circulating protein with pleiotropic ...
Owen, J.S.
core  

Lysogenization, Transduction, and Genetic Recombination in Bacteria

Cold Spring Harbor Symposia on Quantitative Biology, 1958
S E, LURIA, D K, FRASER, J N, ADAMS, J W, BURROUS   +3 more
openaire   +2 more sources