Results 31 to 40 of about 626,396 (286)

CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction

open access: yesmBio, 2018
A powerful contributor to prokaryotic evolution is horizontal gene transfer (HGT) through transformation, conjugation, and transduction, which can be advantageous, neutral, or detrimental to fitness.
Bridget N. J. Watson   +2 more
doaj   +1 more source

Is the bacterial chromosome a mobile genetic element?

open access: yesNature Communications, 2021
An outcome of phage infection, lateral transduction, has been shown to mobilize chromosomal genes between bacterial cells at rates that exceed those of mobile genetic elements such as plasmids.
James P. J. Hall
doaj   +1 more source

lncRNA OR3A4 Promotes the Proliferation and Metastasis of Ovarian Cancer Through KLF6 Pathway

open access: yesFrontiers in Pharmacology, 2021
Aim: Ovarian cancer is a collaborative malignant tumor of the female reproductive system in clinical research. Some clinical studies have shown that OR3A4, which is a cancer-causing lncRNA, plays a major role in promoting the occurrence and development ...
Fangfang Guo   +13 more
doaj   +1 more source

Protein transduction: A novel tool for tissue regeneration [PDF]

open access: yes, 2002
Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Derer W.   +4 more
core   +1 more source

Genetic Control of Signal Transduction in Mouse Melanocytes.

open access: yesJournal of Investigative Dermatology, 1989
At the final step of melanocyte differentiation in mouse hair follicles, the cells produce melanin. The type of melanin they produce is, however, determined by the tissue environment of hair follicles. In wild-type mice, melanocytes located in hair bulbs synthesize eumelanin at the beginning of hair growth.
Takeuchi, Takuji   +2 more
openaire   +2 more sources

Transduction Enhancers Enable Efficient Human Adenovirus Type 5-Mediated Gene Transfer into Human Multipotent Mesenchymal Stromal Cells

open access: yesViruses, 2021
Human multipotent mesenchymal stromal cells (hMSCs) are currently developed as cell therapeutics for different applications, including regenerative medicine, immune modulation, and cancer treatment.
Robin Nilson   +11 more
doaj   +1 more source

GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]

open access: yes, 2013
Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Andras Dinnyes   +6 more
core   +1 more source

Detecting rare gene transfer events in bacterial populations

open access: yesFrontiers in Microbiology, 2014
Horizontal gene transfer (HGT) enables bacteria to access, share, and recombine genetic variation, resulting in genetic diversity that cannot be obtained through mutational processes alone.
Kaare Magne Nielsen   +6 more
doaj   +1 more source

Regulation of tomato fruit ripening [PDF]

open access: yes, 2009
Fruit ripening is a sophisticatedly orchestrated developmental process, unique to plants, that results in major physiological and metabolic changes, ultimately leading to fruit decay and seed dispersal.
Bouzayen, Mondher   +4 more
core   +2 more sources

Crosstalk between Photoreceptor and Sugar Signaling Modulates Floral Signal Transduction

open access: yesFrontiers in Physiology, 2017
Over the past decade, integrated genetic, cellular, proteomic and genomic approaches have begun to unravel the surprisingly crosstalk between photoreceptors and sugar signaling in regulation of floral signal transduction.
Ianis G. Matsoukas
doaj   +1 more source

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