Adaptive response of a gene network to environmental changes by fitness-induced attractor selection. [PDF]
PLoS ONE, 2006 Cells switch between various stable genetic programs (attractors) to accommodate environmental conditions. Signal transduction machineries efficiently convey environmental changes to the gene regulation apparatus in order to express the appropriate ...
Akiko Kashiwagi +3 more
doaj +1 more source
The Biosemiotic Approach in Biology : Theoretical Bases and Applied Models [PDF]
, 2011 Biosemiotics is a growing fi eld that investigates semiotic processes in the living realm in an attempt to combine the fi ndings of the biological sciences and semiotics. Semiotic processes are more or less what biologists have typically referred to as “
El-Hani, Charbel +3 more
core +1 more source
The Mechanosensory Transduction Machinery in Inner Ear Hair Cells.
Annual Review of Biophysics, 2020 Sound-induced mechanical stimuli are detected by elaborate mechanosensory transduction (MT) machinery in highly specialized hair cells of the inner ear.
Wang Zheng, J. R. Holt
semanticscholar +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 Adeno-associated viruses (AAVs) are widely used to deliver genetic material in vivo to distinct cell types such as neurons or glial cells, allowing for targeted manipulation.
Margaret E. Maes +4 more
doaj +1 more source
Perinatal Gene Transfer to the Liver [PDF]
, 2011 The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM +6 more
core +1 more source
Identification of a small molecule for enhancing lentiviral transduction of T cells
Molecular Therapy: Methods & Clinical Development, 2023 Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies.
Paulina Malach +10 more
doaj +1 more source
CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction
mBio, 2018 A powerful contributor to prokaryotic evolution is horizontal gene transfer (HGT) through transformation, conjugation, and transduction, which can be advantageous, neutral, or detrimental to fitness.
Bridget N. J. Watson +2 more
doaj +1 more source
Is the bacterial chromosome a mobile genetic element?
Nature Communications, 2021 An outcome of phage infection, lateral transduction, has been shown to mobilize chromosomal genes between bacterial cells at rates that exceed those of mobile genetic elements such as plasmids.
James P. J. Hall
doaj +1 more source
lncRNA OR3A4 Promotes the Proliferation and Metastasis of Ovarian Cancer Through KLF6 Pathway
Frontiers in Pharmacology, 2021 Aim: Ovarian cancer is a collaborative malignant tumor of the female reproductive system in clinical research. Some clinical studies have shown that OR3A4, which is a cancer-causing lncRNA, plays a major role in promoting the occurrence and development ...
Fangfang Guo +13 more
doaj +1 more source
Information on Transcriptional Regulation and Signal Transduction of _Escherichia coli_ K-12 Integrated in the Database RegulonDB. [PDF]
, 2010 Since its inception, RegulonDB ("http://regulondb.ccg.unam.mx/":http://regulondb.ccg.unam.mx/) has been a database that compiles information about the regulation of transcription initiation of _Escherichia coli_ K-12. However, we are aware that
Alberto Santos-Zavaleta +7 more
core +5 more sources