Results 11 to 20 of about 418,457 (205)
Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements [PDF]
Nature Communications, 2021 It is commonly thought that horizontal transfer of most bacterial chromosomal genes is limited, in comparison with the frequent transfer of mobile genetic elements. Humphrey et al.
Suzanne Humphrey +6 more
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Modeling, Simulation and Application of Bacterial Transduction in Genetic Algorithms [PDF]
Nature Precedings, 2009 At present, all methods in Evolutionary Computation are bioinspired by the fundamental principles of neo-Darwinism, as well as by a vertical gene transfer. Virus transduction is one of the key mechanisms of horizontal gene propagation in microorganisms (e.g. bacteria).
Perales Graván, Carlos +3 more
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Protein transduction: an alternative to genetic intervention? [PDF]
Gene Therapy, 2001 Protein transduction, an emerging technology with potential applications in gene therapy, can best be described as the internalisation of proteins into the cell, from the external environment. This process relies on the inherent property of a small number of proteins and peptides of being able to penetrate the cell membrane. The transducing property of
Ford, K G +3 more
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Host sirtuin 2 as an immunotherapeutic target against tuberculosis
eLife, 2020 Mycobacterium tuberculosis (Mtb) employs plethora of mechanisms to hijack the host defence machinery for its successful survival, proliferation and persistence.
Ashima Bhaskar +5 more
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eLife, 2021 Acoustic overexposure and aging can damage auditory synapses in the inner ear by a process known as synaptopathy. These insults may also damage hair bundles and the sensory transduction apparatus in auditory hair cells.
John Lee +3 more
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Genetics of auditory mechano-electrical transduction [PDF]
Pflügers Archiv - European Journal of Physiology, 2014 The hair bundles of cochlear hair cells play a central role in the auditory mechano-electrical transduction (MET) process. The identification of MET components and of associated molecular complexes by biochemical approaches is impeded by the very small number of hair cells within the cochlea.
Michalski, Nicolas, Petit, Christine
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The implications of alternative pre-mRNA splicing in cell signal transduction
Experimental and Molecular Medicine, 2023 Cells produce multiple mRNAs through alternative splicing, which ensures proteome diversity. Because most human genes undergo alternative splicing, key components of signal transduction pathways are no exception.
Sunkyung Choi, Namjoon Cho, Kee K. Kim
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Expanding applications of chemical genetics in signal transduction [PDF]
Cell Cycle, 2012 Chemical genetics represents an expanding collection of techniques applied to a variety of signaling processes. These techniques use a combination of chemical reporters and protein engineering to identify targets of a signaling enzyme in a global and non-directed manner without resorting to hypothesis-driven candidate approaches.
Scott M, Carlson, Forest M, White
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Genetic Analysis of Abscisic Acid Signal Transduction [PDF]
Plant Physiology, 1997 The scientific origins of ABA can be traced to several independent lines of investigation in the late 1940s (for review, see Addicott and Carns, 1983). In these studies, which in retrospect appear to have involved extracts that were rich in ABA, acidic inhibitors of coleoptile growth were detected that were also correlated with promoting activities on ...
S, Merlot, J, Giraudat
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Protein transduction: A novel tool for tissue regeneration [PDF]
, 2002 Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Cardoso, M. C. +4 more
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