Results 11 to 20 of about 423,895 (267)

GENETIC TRANSDUCTION WITH STAPHYLOPHAGE [PDF]

open access: yesJournal of Bacteriology, 1962
Korman, Ruth Z. (Elmira College, Elmira, N.Y.) and David T. Berman . Genetic transduction with staphylophage. J. Bacteriol. 84: 228–236. 1962.—Transduction by crude lysates obtained by ultraviolet-light induction of phage 53 lysogenic derivatives of Staphylococcus ...
R Z, KORMAN, D T, BERMAN
openaire   +2 more sources

Genetics of auditory mechano-electrical transduction [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2014
The hair bundles of cochlear hair cells play a central role in the auditory mechano-electrical transduction (MET) process. The identification of MET components and of associated molecular complexes by biochemical approaches is impeded by the very small number of hair cells within the cochlea.
Michalski, Nicolas, Petit, Christine
openaire   +3 more sources

Expanding applications of chemical genetics in signal transduction [PDF]

open access: yesCell Cycle, 2012
Chemical genetics represents an expanding collection of techniques applied to a variety of signaling processes. These techniques use a combination of chemical reporters and protein engineering to identify targets of a signaling enzyme in a global and non-directed manner without resorting to hypothesis-driven candidate approaches.
Scott M, Carlson, Forest M, White
openaire   +2 more sources

Genetic Analysis of Abscisic Acid Signal Transduction [PDF]

open access: yesPlant Physiology, 1997
The scientific origins of ABA can be traced to several independent lines of investigation in the late 1940s (for review, see Addicott and Carns, 1983). In these studies, which in retrospect appear to have involved extracts that were rich in ABA, acidic inhibitors of coleoptile growth were detected that were also correlated with promoting activities on ...
S, Merlot, J, Giraudat
openaire   +2 more sources

Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor degenerative environment

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Adeno-associated viruses (AAVs) are widely used to deliver genetic material in vivo to distinct cell types such as neurons or glial cells, allowing for targeted manipulation.
Margaret E. Maes   +4 more
doaj   +1 more source

Identification of a small molecule for enhancing lentiviral transduction of T cells

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies.
Paulina Malach   +10 more
doaj   +1 more source

Genetic Control of Signal Transduction in Mouse Melanocytes.

open access: yesJournal of Investigative Dermatology, 1989
At the final step of melanocyte differentiation in mouse hair follicles, the cells produce melanin. The type of melanin they produce is, however, determined by the tissue environment of hair follicles. In wild-type mice, melanocytes located in hair bulbs synthesize eumelanin at the beginning of hair growth.
Takeuchi, Takuji   +2 more
openaire   +2 more sources

Protein transduction: an alternative to genetic intervention? [PDF]

open access: yesGene Therapy, 2001
Protein transduction, an emerging technology with potential applications in gene therapy, can best be described as the internalisation of proteins into the cell, from the external environment. This process relies on the inherent property of a small number of proteins and peptides of being able to penetrate the cell membrane. The transducing property of
Ford, K G   +3 more
openaire   +3 more sources

CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction

open access: yesmBio, 2018
A powerful contributor to prokaryotic evolution is horizontal gene transfer (HGT) through transformation, conjugation, and transduction, which can be advantageous, neutral, or detrimental to fitness.
Bridget N. J. Watson   +2 more
doaj   +1 more source

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