Immediate and heterogeneous response of the LiaFSR two-component system of Bacillus subtilis to the peptide antibiotic bacitracin. [PDF]
, 2013 Two-component signal transduction systems are one means of bacteria to respond to external stimuli. The LiaFSR two-component system of Bacillus subtilis consists of a regular two-component system LiaRS comprising the core Histidine Kinase (HK) LiaS and ...
Madeleine Leisner (104026) +14 more
core +1 more source
Productive infection and transduction by bacteriophage P1 in the species Salmonella bongori
Electronic Journal of Biotechnology, 2019 Background: Horizontal gene transfer (HGT) is the most important mechanism in the evolution of new genetic capabilities in bacteria, including specific degradative pathways, virulence factors, and resistance to antibiotics.
Natalia A. Riquelme +3 more
doaj +1 more source
Mechanoelectrical transduction-related genetic forms of hearing loss
Current Opinion in Physiology, 2023 Hair cells of the mammalian cochlea are specialized mechanosensory cells that convert mechanical stimuli into electrical signals to initiate the neuronal responses that lead to the perception of sound. The mechanoelectrical transduction (MET) machinery of cochlear hair cells is a multimeric protein complex that consists of the pore forming subunits of ...
Jinsei, Jung, Ulrich, Müller
openaire +3 more sources
Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis.
PLoS Pathogens, 2020 Two component systems (TCSs) are a primary mechanism of signal sensing and response in bacteria. Systematic characterization of an entire TCS could provide a mechanistic understanding of these important signal transduction systems.
Hualiang Pi +10 more
doaj +1 more source
The genetics of signal transduction and the effect of smoking on intrauterine growth [PDF]
International Journal of Epidemiology, 2001 We have studied cytosolic low molecular weight phosphotyrosine phosphatase (cLMWPTP or ACP1) in 364 healthy puerperae from the population of Penne, in 155 diabetic puerperae from the population of Rome and in 349 consecutive normal newborn infants from the population of Rome.
Bottini, E +3 more
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Transduction frequencies of mobile genetic elements.
, 2016 Transduction frequencies of mobile genetic elements.
Joo Youn Park (201915) +6 more
core +1 more source
Phosphorelays provide tunable signal processing capabilities for the cell [PDF]
, 2013 Achieving a complete understanding of cellular signal transduction requires deciphering the relation between structural and biochemical features of a signaling system and the shape of the signal-response relationship it embeds.
Luca Cardelli +23 more
core +1 more source
Genetic Screening for Signal Transduction in the Era of Network Biology [PDF]
Cell, 2007 In contrast to animal-based mutant phenotype assays, recent biochemical and quantitative genetic studies have identified hundreds of potential regulators of known signaling pathways. We discuss the discrepancy between previous models and new data, put forward a different signaling conceptual framework incorporating time-dependent quantitative ...
Friedman, Adam, Perrimon, Norbert
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GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION.
, 2013 Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Polgár, Zsuzsanna +5 more
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Estimation of kinetic rates of MAP kinase activation from experimental data [PDF]
, 2009 Mathematical model is an important tool in systems biology to study the dynamics of biological systems inside the cell. One of the significant challenges in systems biology is the lack of kinetic rates that should be measured in experiments or estimated ...
Tianhai Tian, Tian, T.
core +1 more source