Results 61 to 70 of about 418,457 (205)

Phosphate flow between hybrid histidine kinases CheA₃ and CheS₃ controls Rhodospirillum centenum cyst formation. [PDF]

open access: yesPLoS Genetics, 2013
Genomic and genetic analyses have demonstrated that many species contain multiple chemotaxis-like signal transduction cascades that likely control processes other than chemotaxis.
Kuang He   +3 more
doaj   +1 more source

Modeling, simulation and application of bacterial transduction in genetic algorithms [PDF]

open access: yes, 2013
At present, all methods in Evolutionary Computation are bioinspired by the fundamental principles of neo-Darwinism, as well as by a vertical gene transfer. Virus transduction is one of the key mechanisms of horizontal gene propagation in microorganisms
Lahoz-Beltra, Rafael   +3 more
core  

A novel two-component signal transduction system in propionibacterium acnes and its association with a putative extracellular signalling peptide [PDF]

open access: yes, 2011
Propionibacterium acnes, a resident micro-organism of human skin, is thought to be involved in the development of inflammatory acne, which is an exclusive human disease affecting more than 80% of the whole population. Quorum sensing is the regulation of
Guan, Shuang
core  

Investigation of the Genetics of Cysteineless Mutants of Salmonella typhimurium by Transduction [PDF]

open access: yesJournal of General Microbiology, 1958
SUMMARY: The genetic investigation of forty-three phenotypically classified cysteineless mutants of Salmonella typhimurium by means of transduction suggests that in forty-one of the mutants, strains of similar phenotype result from mutations occurring at a series of sites which form a closely linked group, presumably situated within a single gene locus.
openaire   +2 more sources

Highly efficient intracellular transduction in three-dimensional gradients for programming cell fate [PDF]

open access: yes, 2016
Fundamental behaviour such as cell fate, growth and death are mediated through the control of key genetic transcriptional regulators. These regulators are activated or repressed by the integration of multiple signalling molecules in spatio-temporal ...
Dixon, James E.   +3 more
core   +1 more source

Virus-receptor mediated transduction of dendritic cells by lentiviruses enveloped with glycoproteins derived from Semliki Forest virus. [PDF]

open access: yesPLoS ONE, 2011
Lentiviruses have recently attracted considerable interest for their potential as a genetic modification tool for dendritic cells (DCs). In this study, we explore the ability of lentiviruses enveloped with alphaviral envelope glycoproteins derived from ...
Steven Froelich   +4 more
doaj   +1 more source

Optimization of lentiviral delivery of barcoded anti-CD20 chimeric antigen receptors into rhesus macaque and human natural killer cells

open access: yesMolecular Therapy: Methods & Clinical Development
Natural killer (NK) cells are pivotal in immunosurveillance and hold great potential for immunotherapy due to their ability to target malignant cells. Their low risk of causing graft-versus-host disease (GvHD) post-allogenic transplantation underscores ...
Taha B. Hayal   +10 more
doaj   +1 more source

The fidelity of dynamic signaling by noisy biomolecular networks [PDF]

open access: yes, 2013
Cells live in changing, dynamic environments. To understand cellular decision-making, we must therefore understand how fluctuating inputs are processed by noisy biomolecular networks.
Voliotis Margaritis   +18 more
core   +1 more source

Progress in the use of adeno-associated viral vectors for gene therapy [PDF]

open access: yes, 2004
The development of safe and efficient gene transfer vectors is crucial for the success of gene therapy trials. A viral vector system promising to meet these requirements is based on the apathogenic adeno-associated virus (AAV-2), a member of the ...
Markus Braun-Falco   +5 more
core   +1 more source

Understanding the Dynamics of Gene Regulatory Systems; Characterisation and Clinical Relevance of cis-Regulatory Polymorphisms

open access: yesBiology, 2013
Modern genetic analysis has shown that most polymorphisms associated with human disease are non-coding. Much of the functional information contained in the non-coding genome consists of cis-regulatory sequences (CRSs) that are required to respond to ...
Philip Cowie   +2 more
doaj   +1 more source

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