Results 31 to 40 of about 409,721 (264)

Interplay Between Sugar and Hormone Signalling Pathways Modulate Floral Signal Transduction

Frontiers in Genetics, 2014
The juvenile-to-adult and vegetative-to-reproductive phase transitions are major determinants of plant reproductive success and adaptation to the local environment.
Ianis G. Matsoukas, Ianis G. Matsoukas
doaj   +1 more source

Productive infection and transduction by bacteriophage P1 in the species Salmonella bongori

Electronic Journal of Biotechnology, 2019
Background: Horizontal gene transfer (HGT) is the most important mechanism in the evolution of new genetic capabilities in bacteria, including specific degradative pathways, virulence factors, and resistance to antibiotics.
Natalia A. Riquelme, Marcela F. Leon, Javier A. Santander, James P. Robeson   +3 more
doaj   +1 more source

Mechanoelectrical transduction-related genetic forms of hearing loss

Current Opinion in Physiology, 2023
Hair cells of the mammalian cochlea are specialized mechanosensory cells that convert mechanical stimuli into electrical signals to initiate the neuronal responses that lead to the perception of sound. The mechanoelectrical transduction (MET) machinery of cochlear hair cells is a multimeric protein complex that consists of the pore forming subunits of ...
Jinsei, Jung, Ulrich, Müller
openaire   +3 more sources

Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis.

PLoS Pathogens, 2020
Two component systems (TCSs) are a primary mechanism of signal sensing and response in bacteria. Systematic characterization of an entire TCS could provide a mechanistic understanding of these important signal transduction systems.
Hualiang Pi, Michelle L Chu, Samuel J Ivan, Casey J Latario, Allen M Toth, Sophia M Carlin, Gideon H Hillebrand, Hannah K Lin, Jared D Reppart, Devin L Stauff, Eric P Skaar   +10 more
doaj   +1 more source

The genetics of signal transduction and the effect of smoking on intrauterine growth [PDF]

International Journal of Epidemiology, 2001
We have studied cytosolic low molecular weight phosphotyrosine phosphatase (cLMWPTP or ACP1) in 364 healthy puerperae from the population of Penne, in 155 diabetic puerperae from the population of Rome and in 349 consecutive normal newborn infants from the population of Rome.
Bottini, E, Gloria-Bottini, F, La Torre, M, Lucarini, N   +3 more
openaire   +3 more sources

Prostaglandin E2 as transduction enhancer affects competitive engraftment of human hematopoietic stem and progenitor cells

Molecular Therapy: Methods & Clinical Development, 2023
Ex vivo gene therapy (GT) is a promising treatment for inherited genetic diseases. An ideal transduction protocol should determine high gene marking in long-term self-renewing hematopoietic stem cells (HSCs), preserving their repopulation potential ...
Valentina Poletti, Annita Montepeloso, Danilo Pellin, Alessandra Biffi   +3 more
doaj   +1 more source

Modeling, Simulation and Application of Bacterial Transduction in Genetic Algorithms [PDF]

Nature Precedings, 2009
At present, all methods in Evolutionary Computation are bioinspired by the fundamental principles of neo-Darwinism, as well as by a vertical gene transfer. Virus transduction is one of the key mechanisms of horizontal gene propagation in microorganisms (e.g. bacteria).
Perales Graván, Carlos, Vicente Buendia, Javier de, Castellanos Peñuela, Juan Bautista, Lahoz-Beltra, Rafael   +3 more
openaire   +2 more sources

Depletion of essential mycobacterial gene glmM reduces pathogen survival and induces host-protective immune responses against tuberculosis

Communications Biology
The limitations of TB treatment are the long duration and immune-dampening effects of anti-tuberculosis therapy. The Cell wall plays a crucial role in survival and virulence; hence, enzymes involved in its biosynthesis are good therapeutic targets. Here,
Meetu Agarwal, Ashima Bhaskar, Biplab Singha, Suparba Mukhopadhyay, Isha Pahuja, Archna Singh, Shivam Chaturvedi, Nisheeth Agarwal, Ved Prakash Dwivedi, Vinay Kumar Nandicoori   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Genetic Screening for Signal Transduction in the Era of Network Biology [PDF]

Cell, 2007
In contrast to animal-based mutant phenotype assays, recent biochemical and quantitative genetic studies have identified hundreds of potential regulators of known signaling pathways. We discuss the discrepancy between previous models and new data, put forward a different signaling conceptual framework incorporating time-dependent quantitative ...
Friedman, Adam, Perrimon, Norbert
openaire   +4 more sources