Results 31 to 40 of about 418,457 (205)

Is the bacterial chromosome a mobile genetic element?

Nature Communications, 2021
An outcome of phage infection, lateral transduction, has been shown to mobilize chromosomal genes between bacterial cells at rates that exceed those of mobile genetic elements such as plasmids.
James P. J. Hall
doaj   +1 more source

Transduction Enhancers Enable Efficient Human Adenovirus Type 5-Mediated Gene Transfer into Human Multipotent Mesenchymal Stromal Cells

Viruses, 2021
Human multipotent mesenchymal stromal cells (hMSCs) are currently developed as cell therapeutics for different applications, including regenerative medicine, immune modulation, and cancer treatment.
Robin Nilson, Olivia Lübbers, Linus Weiß, Karmveer Singh, Karin Scharffetter-Kochanek, Markus Rojewski, Hubert Schrezenmeier, Philip Helge Zeplin, Wolfgang Funk, Lea Krutzke, Stefan Kochanek, Astrid Kritzinger   +11 more
doaj   +1 more source

Lentiviral manipulation of gene expression in human adult and embryonic stem cells [PDF]

, 2006
Human stem cells could revolutionize the field of medicine by providing a diverse range of cell types for tissue replacement therapies and drug discovery.
Joanne Crossley, Crossley, J., Andrew Godfrey, Takeuchi, Y., Clements, M.O., Boshoff, C., Godfrey, A., Mark O. Clements, Sam J. Wilson, Wilson, S.J., Yasu Takeuchi, Chris Boshoff   +11 more
core   +1 more source

Phage ϕC2 Mediates Transduction of Tn6215, Encoding Erythromycin Resistance, between Clostridium difficile Strains

mBio, 2013
In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10−6 per PFU. The transductants were lysogenic for ϕC2 and contained the erm(B) gene
Shan Goh, Haitham Hussain, Barbara J. Chang, Warren Emmett, Thomas V. Riley, Peter Mullany   +5 more
doaj   +1 more source

Crosstalk between Photoreceptor and Sugar Signaling Modulates Floral Signal Transduction

Frontiers in Physiology, 2017
Over the past decade, integrated genetic, cellular, proteomic and genomic approaches have begun to unravel the surprisingly crosstalk between photoreceptors and sugar signaling in regulation of floral signal transduction.
Ianis G. Matsoukas
doaj   +1 more source

lncRNA OR3A4 Promotes the Proliferation and Metastasis of Ovarian Cancer Through KLF6 Pathway

Frontiers in Pharmacology, 2021
Aim: Ovarian cancer is a collaborative malignant tumor of the female reproductive system in clinical research. Some clinical studies have shown that OR3A4, which is a cancer-causing lncRNA, plays a major role in promoting the occurrence and development ...
Fangfang Guo, Fangfang Guo, Jianan Du, Jianan Du, Lingling Liu, Lingling Liu, Yawei Gou, Yawei Gou, Mingming Zhang, Mingming Zhang, Wei Sun, Wei Sun, Hongmei Yu, Xueqi Fu   +13 more
doaj   +1 more source

The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways [PDF]

, 2012
The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and ...
Tina Jaeger (158216), Jenal Urs, Jacob G. Malone (158210), Blanka Andrea, Pablo Manfredi, Andrea Blanka, Guy R. Cornelis, Jacob G. Malone, Jaeger Tina, Cornelis Guy R., Bos, R., Manfredi, Pablo, Jacob G Malone, Dötsch, A., Jaeger, T., Blanka, A., Pablo Manfredi (158219), Cornelis, Guy R, Manfredi, P., Bos Raphael, Andrea Blanka (158227), Raphael Bos (158229), Jenal, Urs, Jaeger, Tina, Tina Jaeger, Malone, Jacob G., Urs Jenal (37942), Jenal, U., Blanka, Andrea, Malone Jacob G., Dötsch Andreas, Susanne Häussler (158235), Urs Jenal, Häussler, S., Andreas Dötsch, Cornelis, Guy R., Susanne Häussler, Häussler, Susanne, Manfredi Pablo, Häussler Susanne, Raphael Bos, Guy R. Cornelis (158232), Guy R Cornelis, Malone, Jacob G, Dötsch, Andreas, Cornelis, G. R., Andreas Dötsch (158223), Bos, Raphael, Malone, J. G.   +48 more
core   +1 more source

Transduction Analysis of the Genetic Determinants for Chloramphenicol Resistance in Staphylococci [PDF]

Japanese Journal of Microbiology, 1970
ABSTRACTA genetic analysis of resistance to chloramphenicol (CM) in Staphylococcus aureus S1337 was carried out through transduction. About 3 to 18% of the transductants jointly acquired resistance to both tetracycline (TC) and CM, even when singly selected for either CM‐ or TC‐resistance.
M, Inoue, H, Hashimoto, S, Yamagishi, S, Mitsuhashi   +3 more
openaire   +2 more sources

Interplay Between Sugar and Hormone Signalling Pathways Modulate Floral Signal Transduction

Frontiers in Genetics, 2014
The juvenile-to-adult and vegetative-to-reproductive phase transitions are major determinants of plant reproductive success and adaptation to the local environment.
Ianis G. Matsoukas, Ianis G. Matsoukas
doaj   +1 more source

STCDB: Signal Transduction Classification Database

, 2003
Chen M, Lin S, Hofestädt R. STCDB: Signal Transduction Classification Database. Nucleic Acids Research. 2004;32(90001):D456-D458.The Signal Transduction Classification Database (STCDB) is a database of information relative to the classification of signal
Chen, Ming, Susana Lin, Hofestädt, Ralf, Ralf Hofestaedt, Lin, Susana, Ming Chen   +5 more
core   +1 more source