The genetics of signal transduction and the effect of smoking on intrauterine growth [PDF]
International Journal of Epidemiology, 2001 We have studied cytosolic low molecular weight phosphotyrosine phosphatase (cLMWPTP or ACP1) in 364 healthy puerperae from the population of Penne, in 155 diabetic puerperae from the population of Rome and in 349 consecutive normal newborn infants from the population of Rome.
E, Bottini +3 more
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Co-expression networks in generation of induced pluripotent stem cells. [PDF]
, 2016 We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for
Coppola, Giovanni +6 more
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Transduction Analysis of the Genetic Determinants for Chloramphenicol Resistance in Staphylococci [PDF]
Japanese Journal of Microbiology, 1970 ABSTRACTA genetic analysis of resistance to chloramphenicol (CM) in Staphylococcus aureus S1337 was carried out through transduction. About 3 to 18% of the transductants jointly acquired resistance to both tetracycline (TC) and CM, even when singly selected for either CM‐ or TC‐resistance.
M, Inoue +3 more
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Interplay Between Sugar and Hormone Signalling Pathways Modulate Floral Signal Transduction
Frontiers in Genetics, 2014 The juvenile-to-adult and vegetative-to-reproductive phase transitions are major determinants of plant reproductive success and adaptation to the local environment.
Ianis G. Matsoukas, Ianis G. Matsoukas
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Developmental signal transduction pathways uncovered by genetic suppressors [PDF]
Proceedings of the National Academy of Sciences, 1996 We have found conditions for saturation mutagenesis by restriction enzyme mediated integration that result in plasmid tagging of disrupted genes. Using this method we selected for mutations in genes that act at checkpoints downstream of the intercellular signaling system that controls encapsulation in Dictyostelium ...
G, Shaulsky, R, Escalante, W F, Loomis
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Productive infection and transduction by bacteriophage P1 in the species Salmonella bongori
Electronic Journal of Biotechnology, 2019 Background: Horizontal gene transfer (HGT) is the most important mechanism in the evolution of new genetic capabilities in bacteria, including specific degradative pathways, virulence factors, and resistance to antibiotics.
Natalia A. Riquelme +3 more
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Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis.
PLoS Pathogens, 2020 Two component systems (TCSs) are a primary mechanism of signal sensing and response in bacteria. Systematic characterization of an entire TCS could provide a mechanistic understanding of these important signal transduction systems.
Hualiang Pi +10 more
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The genome and transcriptome of Trichormus sp NMC-1: insights into adaptation to extreme environments on the Qinghai-Tibet Plateau [PDF]
, 2016 The Qinghai-Tibet Plateau (QTP) has the highest biodiversity for an extreme environment worldwide, and provides an ideal natural laboratory to study adaptive evolution.
A Stamatakis +53 more
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Molecular Therapy: Methods & Clinical Development, 2023 Ex vivo gene therapy (GT) is a promising treatment for inherited genetic diseases. An ideal transduction protocol should determine high gene marking in long-term self-renewing hematopoietic stem cells (HSCs), preserving their repopulation potential ...
Valentina Poletti +3 more
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A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]
, 2018 open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...
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