Results 11 to 20 of about 1,297,985 (274)

Comparison of the Transduction Capacity of AAV5 and AAV PHP.eB Serotypes in Hippocampus Astroglia

open access: yesNeuroglia, 2023
In the present study, we compared the astrocyte-transducing potential of the relatively novel engineered AAV PHP.eB serotype and the well-examined conventional AAV5 serotype.
Anastasia Borodinova   +2 more
doaj   +1 more source

High-dimensional sequence transduction [PDF]

open access: yes, 2012
We investigate the problem of transforming an input sequence into a high-dimensional output sequence in order to transcribe polyphonic audio music into symbolic notation. We introduce a probabilistic model based on a recurrent neural network that is able
Bengio, Yoshua   +2 more
core   +2 more sources

Isolation of tissue-resident endothelial stem cells and their use in regenerative medicine

open access: yesInflammation and Regeneration, 2019
Background During sprouting angiogenesis, stalk cells, localized behind tip cells, generate endothelial cells (ECs) for the elongation of new vessels.
Tomohiro Iba   +5 more
doaj   +1 more source

Modeling the Electrostatic Actuation of Nanomechanical Pillar Dimers

open access: yesFrontiers in Mechanical Engineering, 2021
With their unparalleled mass sensitivity, enabling single-molecule mass spectrometry, nanomechanical resonators have the potential to considerably improve existing sensor technology.
Andreas Kainz   +3 more
doaj   +1 more source

Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes

open access: yesMolecular Therapy: Methods & Clinical Development, 2017
Ex vivo transduction of human CD34+ hematopoietic stem/progenitor cells (hCD34+ HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results.
Claudia Piovan   +10 more
doaj   +1 more source

AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery

open access: yesViruses, 2023
Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity.
Darrick L. Yu   +7 more
doaj   +1 more source

Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]

open access: yes, 2003
A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM   +4 more
core   +1 more source

Tropism and transduction of oncolytic adenovirus vectors in prostate cancer therapy

open access: yesFrontiers in Bioscience-Landmark, 2021
Oncolytic adenovirus has been applied in cancer therapy because of several advantages such as cost-effective production, high transduction efficiency and low toxicity.
Chuang Wu   +6 more
doaj   +1 more source

Simondon and Bohm between determinism and indeterminism [PDF]

open access: yesFilozofija i Društvo, 2022
The radical redefinition of the landscape of physics that followed the contributions of Niels Bohr and Werner Heisenberg at the start of the 20th century led to plethora [of] new perspectives on age-old metaphysical questions on determinism and ...
Jovićević Andrej
doaj   +1 more source

Feedback Enhanced Sensitivity in Optomechanics: Surpassing the Parametric Instability Barrier [PDF]

open access: yes, 2011
The intracavity power, and hence sensitivity, of optomechanical sensors is commonly limited by parametric instability. Here we characterize the parametric instability induced sensitivity degradation in a micron scale cavity optomechanical system ...
Andersen, Ulrik L.   +3 more
core   +3 more sources

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