Results 11 to 20 of about 1,277,434 (275)
Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]
, 2017 The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C +3 more
core +1 more source
Molecular Therapy: Methods & Clinical Development, 2017 Ex vivo transduction of human CD34+ hematopoietic stem/progenitor cells (hCD34+ HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results.
Claudia Piovan +10 more
doaj +1 more source
High-dimensional sequence transduction [PDF]
, 2012 We investigate the problem of transforming an input sequence into a high-dimensional output sequence in order to transcribe polyphonic audio music into symbolic notation. We introduce a probabilistic model based on a recurrent neural network that is able
Bengio, Yoshua +2 more
core +2 more sources
Viruses, 2023 Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity.
Darrick L. Yu +7 more
doaj +1 more source
Tropism and transduction of oncolytic adenovirus vectors in prostate cancer therapy
Frontiers in Bioscience-Landmark, 2021 Oncolytic adenovirus has been applied in cancer therapy because of several advantages such as cost-effective production, high transduction efficiency and low toxicity.
Chuang Wu +6 more
doaj +1 more source
Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]
, 2003 A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM +4 more
core +1 more source
eLife, 2023 Melanopsin signaling within intrinsically photosensitive retinal ganglion cell (ipRGC) subtypes impacts a broad range of behaviors from circadian photoentrainment to conscious visual perception.
Ely Contreras +4 more
doaj +1 more source
Efficient Transduction and Expansion of Ovine Macrophages for Gene Therapy Implementations
Veterinary Sciences, 2018 A number of bacteria provoking zoonotic diseases present intracellular survival and a host cell tropism limited to the monocyte/macrophage lineage. Thus, infection is rendered difficult to eradicate, causing chronic inflammatory reactions to the host and
Garyfalia Karponi +3 more
doaj +1 more source
Simondon and Bohm between determinism and indeterminism [PDF]
Filozofija i Društvo, 2022 The radical redefinition of the landscape of physics that followed the contributions of Niels Bohr and Werner Heisenberg at the start of the 20th century led to plethora [of] new perspectives on age-old metaphysical questions on determinism and ...
Jovićević Andrej
doaj +1 more source
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada +9 more
core +1 more source