Results 21 to 30 of about 1,277,434 (275)

Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells

open access: yesJournal of Lipid Research, 2001
3T3-L1 cells have been used as a model to study the differentiation and physiology of adipocytes. Exogenous expression of proteins in these cells offers the prospect of understanding the protein's function(s) in adipose tissue.
David J. Orlicky   +2 more
doaj   +1 more source

Feedback Enhanced Sensitivity in Optomechanics: Surpassing the Parametric Instability Barrier [PDF]

open access: yes, 2011
The intracavity power, and hence sensitivity, of optomechanical sensors is commonly limited by parametric instability. Here we characterize the parametric instability induced sensitivity degradation in a micron scale cavity optomechanical system ...
Andersen, Ulrik L.   +3 more
core   +3 more sources

Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant

open access: yesMolecular Therapy: Nucleic Acids, 2014
HIV-1 derived vectors are among the most efficient for gene transduction in mammalian tissues. As the parent virus, they carry out vector genome insertion into the host cell chromatin.
Muhammad Qamar Saeed   +17 more
doaj   +1 more source

Cognitive Phonetics: The Transduction of Distinctive Features at the Phonology-Phonetics Interface

open access: yesBiolinguistics, 2018
We propose that the interface between phonology and phonetics is mediated by a transduction process that converts elementary units of phonological computation, features, into temporally coordinated neuromuscular patterns, called ‘True Phonetic ...
Veno Volenec, Charles Reiss
doaj   +1 more source

A Short Introduction to Bacteriophages

open access: yesTrends in Peptide and Protein Sciences, 2016
First discovered in the 19th century, bacteriophages (phages) are bacterial viruses and the most widespread entities on earth. Phages have multiple important roles in maintaining the bacterial population, carbon cycling, bacterial pathogenicity, and ...
Ramin Mazaheri Nezhad Fard
doaj   +1 more source

Genetic engineering of human and mouse CD4+ and CD8+ Tregs using lentiviral vectors encoding chimeric antigen receptors

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
The last decade has seen a significant increase of cell therapy protocols using effector T cells (Teffs) in particular, but also, more recently, non-engineered and expanded polyclonal regulatory T cells (Tregs) to control pathological immune responses ...
Nadège Vimond   +4 more
doaj   +1 more source

Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj [PDF]

open access: yes, 2009
Background: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors.
Silke Schüle   +61 more
core   +5 more sources

Transfer of antibiotic resistance in Staphylococcus aureus [PDF]

open access: yes, 2017
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob   +2 more
core   +1 more source

AlphaPeptDeep: a modular deep learning framework to predict peptide properties for proteomics

open access: yesNature Communications, 2022
Deep learning (DL) has been frequently used in mass spectrometry-based proteomics but there is still a lot of potential. Here, the authors develop a framework that enables building DL models to predict arbitrary peptide properties with only a few lines ...
Wen-Feng Zeng   +8 more
doaj   +1 more source

Transduction and Meaning–Making Issues Within Multimodal Messages [PDF]

open access: yes, 2015
This paper analyzes transduction as an action of transposing information from one mode to another within the communication process and its implications in terms of meaning and coherence of a multimodal message.
Culache, Oana
core   +1 more source

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