Results 41 to 50 of about 1,277,434 (275)
Self-organization of signal transduction
, 2013 We propose a model of parameter learning for signal transduction, where the objective function is defined by signal transmission efficiency. We apply this to learn kinetic rates as a form of evolutionary learning, and look for parameters which satisfy ...
Scheler, Gabriele
core +2 more sources
Mechano-transduction: from molecules to tissues. [PDF]
, 2014 External forces play complex roles in cell organization, fate, and homeostasis. Changes in these forces, or how cells respond to them, can result in abnormal embryonic development and diseases in adults.
Dunn, Alexander R +3 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
On the Monadic Second-Order Transduction Hierarchy [PDF]
, 2009 We compare classes of finite relational structures via monadic second-order transductions. More precisely, we study the preorder where we set C \subseteq K if, and only if, there exists a transduction {\tau} such that C\subseteq{\tau}(K).
A. Blumensath +17 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Viruses, 2022 A transduced mouse model of SARS-CoV-2 infection was established using Balb/c mice. This was achieved through the adenovirus-vectored delivery of the hACE2 gene, to render the mice transiently susceptible to the virus.
Sophie J. Smither +9 more
doaj +1 more source
Distribution matching for transduction [PDF]
, 2009 Many transductive inference algorithms assume that distributions over training and test estimates should be related, e.g. by providing a large margin of separation on both sets.
Petterson, James +2 more
core +1 more source
Streamability of nested word transductions
, 2019 We consider the problem of evaluating in streaming (i.e., in a single left-to-right pass) a nested word transduction with a limited amount of memory. A transduction T is said to be height bounded memory (HBM) if it can be evaluated with a memory that ...
Filiot, Emmanuel +3 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A amplificação nos processos de informação
Trans/Form/AçãoResumo: Esta é a tradução do texto “L’amplification dans les processus d’information”, conferência ministrada por Gilbert Simondon em 1962, no Colloque de Royaumont sobre “o conceito de informação na ciência contemporânea (Le concept d’information dans ...
Pedro Peixoto Ferreira, Evandro Smarieri
doaj +1 more source