Results 131 to 140 of about 83,780 (258)

Synthetic super-enhancers enable precision viral immunotherapy. [PDF]

Nature
Koeber U, Matjusaitis M, Alfazema N, Furlong K, Wang Z, White R, Hamdan A, Dewari P, Morisse G, Navarette M, Willis R, Wang J, Clark MP, Jacinto de Sousa C, Hong HI, Sheraz S, Southgate B, Cholewa-Waclaw J, Gogolok S, Morrison GM, Cancino FG, Robertson F, Williams A, Rosser SJ, Brennan PM, Sieger D, Soufi A, Quezada SA, Pollard SM.   +28 more
europepmc   +1 more source

n‐Type Semiconductor Hydrogels for Tunable Organic Electrochemical Transistors Operation and Evaporation‐Driven Synergistic Energy Harvesting and Thermal Management

Advanced Functional Materials, EarlyView.
This study develops a tunable n‐OSC hydrogel (PBFDO‐PAAc) platform with a tunable porous network and thermoelectric properties. It demonstrates the first report of n‐OSC hydrogels for evaporation‐driven hydrovoltaic‐thermoelectric electricity generation as well as chemically dedoping‐mediated OECT working mode reconfiguration. This work expands n‐OSCs’
Zhenli Zhou, Cong Huang, Haohong Jiang, Yuhao Jiang, Yaoyao Zhu, Boyuan Li, Yi Wang, Enna Ha, Ni Zhao, Shu‐Jen Wang   +9 more
wiley   +1 more source

Achieving cell-type specific transduction with adeno-associated viral vectors in pigeons. [PDF]

Curr Res Neurobiol
Tuff JM, Haselhuhn K, Surdin T, Herlitze S, Ziegler M, Güntürkün O, Rook N.   +6 more
europepmc   +1 more source

An Edible Chitosan‐Based Acoustic Sensor for Sound‐Responsive Actuation in Edible Robots

Advanced Functional Materials, EarlyView.
This study introduces an edible acoustic sensor for robotic food and edible robotics. Built from a chitosan piezoelectric film between gold electrodes, the sensor enables acoustic communication through ON/OFF keying. Integrated into an edible robot with pneumatically actuated arms and neck, it responds to high‐frequency tones.
Valerio Francesco Annese, Bokeon Kwak, Gaia de Marzo, Giulia Coco, Valentina Antonaci, Leonardo Lamanna, Massimo De Vittorio, Dario Floreano, Mario Caironi   +8 more
wiley   +1 more source

STARR-CRAAVT: A platform to identify cell type-specific regulatory elements for next-generation gene therapy. [PDF]

iScience
Becker R, Choudhury P, Oti M, Fouani Y, Strobel B, Ketterer S, Rumpel S, Park J, Kreuz S, Maier U, Michelfelder S, Schön C.   +11 more
europepmc   +1 more source

Hierarchical Collagen Nanofiber Gels Recapitulate a Physiologically Relevant Tumor Stromal Microenvironment

Advanced Healthcare Materials, EarlyView.
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki, Tomoyuki Suezawa, Shiro Kitano, Ryohei Katayama, Michiya Matsusaki   +4 more
wiley   +1 more source

Neuritin1 Cis-Regulatory Elements Enable Gene Expression Preferentially in Retinal Ganglion Cells. [PDF]

Invest Ophthalmol Vis Sci
Talla V, Koilkonda R, Kinane C, Panchal M, Khuu T, Park KK.   +5 more
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia. [PDF]

Sci Adv
Priebe V, Galvan B, Drakul A, Margelisch N, Aguadé-Gorgorió J, Walavalkar K, Huang Y, Mikkola HKA, Bornhauser B, Santoro R, Bourquin JP.   +10 more
europepmc   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source