Results 71 to 80 of about 145,799 (355)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Comprehensive Comparison of Baculoviral and Plasmid Gene Delivery in Mammalian Cells
Viruses(1) Recombinant protein production in mammalian cells is either based on transient transfection processes, often inefficient and underlying high batch-to-batch variability, or on laborious generation of stable cell lines.
Maria Toth +5 more
doaj +1 more source
Long-distance effects of insertional mutagenesis. [PDF]
PLoS ONE, 2011 Most common systems of genetic engineering of mammalian cells are associated with insertional mutagenesis of the modified cells. Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects.
Ruchi Singhal +3 more
doaj +1 more source
Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages
Frontiers in Immunology, 2021 Mitofusin 2 (MFN2) is a mitochondrial outer membrane GTPase, which modulates mitochondrial fusion and affects the interaction between endoplasmic reticulum and mitochondria.
Vera Khodzhaeva +9 more
doaj +1 more source
MPRAnalyze: statistical framework for massively parallel reporter assays. [PDF]
, 2019 Massively parallel reporter assays (MPRAs) can measure the regulatory function of thousands of DNA sequences in a single experiment. Despite growing popularity, MPRA studies are limited by a lack of a unified framework for analyzing the resulting data ...
Ahituv, Nadav +5 more
core
Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]
, 2019 Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate ...
Bai, Fan +6 more
core +3 more sources
Enhanced transduction methods for electrostatically driven MEMS resonators [PDF]
TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference, 2009 Electrically addressed silicon bulk acoustic wave microresonators offer high Q solutions for applications in sensing and signal processing. However, the electrically transduced motional signal is often swamped by parasitic feedthrough in hybrid technologies. With the aim of enhancing the ratio of the motional to feedthrough current at nominal operating
Lin, Angel T-H +3 more
openaire +2 more sources
An evaluation of approaches for enhancing inductive learning with a transductive view
Journal of Physics: Conference Series, 2022 AbstractAvailability of enough labeled data is a challenge for most inductive learners who try to generalize based on limited labeled dataset. A traditional semi-supervised approach for the same problem attempts to approach it by methods such as wrapping multiple inductive learners on derived pseudo-labels, unsupervised feature extraction or suitable ...
T N Lokesh Kumar, Bhaskarjyoti Das
openaire +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source