Results 51 to 60 of about 760 (163)

Transferosomes: A Novel Approach To Drug Delivery

, 2023
The development of innovative medicine delivery methods is currently generating renewed interest. These innovative drug delivery technologies also include vesicular drug delivery systems. The permeability of the skin, or TDDS, is extremely impermeable to macromolecules and hydrophilic medicines but permeable to small molecules and lipophilic ...
openaire   +1 more source

Design and Characterization of a Transethosome‐Based Gel for Cutaneous Administration of Genistein

Journal of Nanotechnology, Volume 2026, Issue 1, 2026.
In this study, lipid nanovesicular systems such as ethosome and transethosome dispersions were studied as potential vehicles for the cutaneous administration of genistein, an isoflavone with antioxidant and chemopreventive properties. The lipophilicity of genistein requires specialized delivery systems suitable for transdermal administration. Genistein
Federico Santamaria, Ilenia Gugel, Valentyn Dzyhovskyi, Paolo Moretti, Paolo Mariani, Alessia Pepe, Maria Grazia Ortore, Michal Rawski, Anna Baldisserotto, Stefano Manfredini, Alice Casoni, Mascia Benedusi, Giuseppe Valacchi, Elisabetta Esposito, Ameeduzzafar Zafar   +14 more
wiley   +1 more source

Synthesis and Investigation of Apoptosis and Anti‐Metastatic Effects of Niosomes Containing the Extract of Colchicum kotschyi in MCF‐7

Natural Sciences, Volume 5, Issue 4, October 2025.
This graphical abstract shows the synthesis and biological effects of niosomes loaded with Colchicum kotschyi extract on MCF‐7 breast cancer cells. The extract was encapsulated via the thin‐film hydration method to form stable, spherical niosomes. The formulation enhanced cytotoxicity, induced apoptosis, and suppressed metastasis by increasing Bax and ...
Mahsa Kavousi, Maryam Kazemi Hatami
wiley   +1 more source

Preparation and Evaluation of Dapagliflozin Propanediol Monohydrate-Loaded Transferosomal Dispersion for Transdermal Delivery

Iraqi Journal of Pharmaceutical Sciences
The transdermal route of drug delivery has received significant attention in pharmaceutical research due to its ability to overcome many challenges associated with oral medication administration, including the ability to bypass first-pass metabolism ...
Mohsin Hussein Abdulameer, Nidhal Khazaal Maraie   +1 more
doaj   +1 more source

Development and evaluation of ultradeformable vesicles loaded transdermal film of boswellic acid

Future Journal of Pharmaceutical Sciences, 2022
Background Boswellic acid (BA), a phytoconstituent obtained from Boswellia serrata, suffers from several limitations after oral administration such as poor systemic absorption, high first-pass metabolism and high frequency of dose requirement, which ...
Umang Varia, Disha Joshi, Mukesh Jadeja, Hitesh Katariya, Krunal Detholia, Vishwa Soni   +5 more
doaj   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, Volume 42, Issue 10, October 2025.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

Pharmaceutical development of etodolac transfersomal gel for topical drug delivery system in rheumatoid arthritis

Journal of Applied Pharmaceutical Research
Background: Transferosomes provide delivery of the drug into systemic circulation via the skin as a topical delivery system. So, this study started with the objective of formulating Etodolac transfersomal gel to enhance its skin permeation.
Ashwini Bachhav, Prashant L Pingale, Chandrashekhar D Upasani   +2 more
doaj   +1 more source

DESIGN AND CHARACTERIZATION OF TRANSFEROSOMAL GEL OF REPAGLINIDE

International Research Journal of Pharmacy, 2015
The main aim of current investigation is to formulate and evaluate transferosomal gel for effective transdermal delivery of r epaglinide. Repaglinide is an oral anti hyperglycemic agent used for the treatment of non - insulin - dependent diabetes mellitu s ( NIDDM ).
Vijaya Laxmi M, Md Zafaruddin, Vijaya Kuchana   +2 more
openaire   +1 more source

Advancements in Dissolving Microneedles for Effective Transdermal Delivery in Rheumatoid Arthritis Treatment

Advanced Materials Interfaces, Volume 12, Issue 18, September 22, 2025.
Rheumatoid arthritis, a chronic inflammatory joint disease, faces limitations with conventional therapies. Dissolving microneedles (DMNs) enable biocompatible, high‐capacity transdermal drug delivery. However, skin elasticity challenges their strength, limiting drug release depth.
Wangrui Peng, MeeiChyn Goh, Jie Lan, Meng Du, Zhiyi Chen   +4 more
wiley   +1 more source

Transdermal Liposomal Delivery Systems: Advantages, Applications, Challenges, and Prospects

MedComm – Biomaterials and Applications, Volume 4, Issue 3, September 2025.
This review summarizes advances in liposomal transdermal systems (ethosomes, transfersomes, niosomes, pharmacosomes), focusing on their mechanisms, clinical potential in disease therapy, and future challenges to enhance translation and innovation.
Hui Xing, Ziyi Zhao, Xiaoxu Zhu, Zhi Zhang, Guowei Li, Dong Ma   +5 more
wiley   +1 more source