Results 1 to 10 of about 279 (98)

Development and In Vivo Evaluation of Multidrug Ultradeformable Vesicles for the Treatment of Skin Inflammation [PDF]

Pharmaceutics, 2019
The aim of this work was to evaluate the effect of two chemically different edge activators, i.e., Tween® 80 and sodium deoxycholate, on (i) the physical, mechanical, and biological properties of ultradeformable vesicles, and (ii) the administration of naproxen sodium-loaded multidrug ultradeformable vesicles for the transdermal route in order to ...
Roberto Molinaro, Antonia Mancuso, Donato Cosco   +2 more
exaly   +6 more sources

Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes. [PDF]

Int J Nanomedicine, 2015
Andreia Ascenso,1 Sara Raposo,1 Cátia Batista,2 Pedro Cardoso,2 Tiago Mendes,2 Fabíola Garcia Praça,3 Maria Vitória Lopes Badra Bentley,3 Sandra Simões1 1Instituto de Investigação do Medicamento (iMed ...
Ascenso A, Raposo S, Batista C, Cardoso P, Mendes T, Praça FG, Bentley MV, Simões S.   +7 more
europepmc   +6 more sources

Ultradeformable Vesicles for Wound Healing: Ethosomes, Transferosomes, and Transethosomes in Topical Drug Delivery. [PDF]

Pharmaceutics
Wound healing is a dynamic and multifaceted biological process involving hemostasis, inflammation, proliferation, and tissue remodeling. Topical therapy is widely preferred for wound management due to its localized action and reduced systemic adverse ...
Jacob S, Varkey NR, Nair AB.
europepmc   +4 more sources

Ammonium Glycyrrhizinate and Bergamot Essential Oil Co-Loaded Ultradeformable Nanocarriers: An Effective Natural Nanomedicine for In Vivo Anti-Inflammatory Topical Therapies. [PDF]

Biomedicines, 2022
Bergamot essential oil (BEO) and Ammonium glycyrrhizinate (AG), naturally derived compounds, have remarkable anti-inflammatory properties, thus making them suitable candidates for the treatment of skin disorders.
Cristiano MC, d'Avanzo N, Mancuso A, Tarsitano M, Barone A, Torella D, Paolino D, Fresta M.   +7 more
europepmc   +2 more sources

Development and evaluation of ultradeformable vesicles loaded transdermal film of boswellic acid

Future Journal of Pharmaceutical Sciences, 2022
Background Boswellic acid (BA), a phytoconstituent obtained from Boswellia serrata, suffers from several limitations after oral administration such as poor systemic absorption, high first-pass metabolism and high frequency of dose requirement, which ...
Umang Varia, Disha Joshi, Mukesh Jadeja, Hitesh Katariya, Krunal Detholia, Vishwa Soni   +5 more
doaj   +2 more sources

Sulforaphane-Loaded Ultradeformable Vesicles as A Potential Natural Nanomedicine for the Treatment of Skin Cancer Diseases. [PDF]

Pharmaceutics, 2019
Sulforaphane is a multi-action drug and its anticancer activity is the reason for the continuous growth of attention being paid to this drug. Sulforaphane shows an in vitro antiproliferative activity against melanoma and other skin cancer diseases.
Cristiano MC, Froiio F, Spaccapelo R, Mancuso A, Nisticò SP, Udongo BP, Fresta M, Paolino D.   +7 more
europepmc   +3 more sources

Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluation. [PDF]

Drug Deliv, 2021
Voriconazole (VCZ) is a well-known broad spectrum triazole antifungal, mainly used orally and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for the topical treatment of ocular fungal keratitis.
Fahmy AM, Hassan M, El-Setouhy DA, Tayel SA, Al-Mahallawi AM.   +4 more
europepmc   +2 more sources

Development of Ultradeformable Liposomes with Fatty Acids for Enhanced Dermal Rosmarinic Acid Delivery. [PDF]

Pharmaceutics, 2021
This study aimed to develop ultradeformable liposomes (ULs) with fatty acids, namely, oleic, linoleic, and linolenic acid, to improve the skin penetration of rosmarinic acid.
Subongkot T, Ngawhirunpat T, Opanasopit P.   +2 more
europepmc   +2 more sources

Inhibition of skin inflammation by baicalin ultradeformable vesicles

International Journal of Pharmaceutics, 2016
The topical efficacy of baicalin, a natural flavonoid isolated from Scutellaria baicalensis Georgi, which has several beneficial properties, such as antioxidative, antiviral, anti-inflammatory and antiproliferative, is hindered by its poor aqueous solubility and low skin permeability.
Silvia Mir-Palomo, Amparo Nacher, Octavio Díez-Sales   +2 more
exaly   +6 more sources

Increased skin permeation efficiency of imperatorin via charged ultradeformable lipid vesicles for transdermal delivery

International Journal of Nanomedicine, 2018
Hongwei Lin,1,2 Qingchun Xie,1,2 Xin Huang,1,2 Junfeng Ban,1,2 Bo Wang,1,2 Xing Wei,3 Yanzhong Chen,1,2 Zhufen Lu1,2 1Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangdong Pharmaceutical University, Guangzhou, People’s ...
Lin HW, Xie QC, Huang X, Ban JF, Wang B, Wei X, Chen YZ, Lu ZF   +7 more
doaj   +6 more sources