Results 11 to 20 of about 298 (115)
Ultradeformable phospholipid vesicles as a drug delivery system: a review
Maria Jose Morilla, Eder Lilia RomeroNanomedicine Research Program, Department of Science and Technology, National University of Quilmes, Buenos Aires, Argentina Abstract: Ultradeformable vesicles are highly deformable (elastic/flexible) liposomes made of phospholipids plus highly mobile hydrophilic detergents capable of penetrating the intact skin ...
Eder Lilia Romero, Maria JOSÉ Morilla
exaly +6 more sources
Whether ultradeformable vesicles pass intact through the stratum corneum and can promote the transdermal absorption of any substance remain open questions. This paper presents different experimental approaches, based on the use of calcein as hydrophilic fluorescent marker, to probe the physicochemical and pharmacokinetic characteristics of these ...
Lucas Antonio Miranda Ferreira +1 more
exaly +3 more sources
Fabrication and application of targeted ciprofloxacin nanocarriers for the treatment of chronic bacterial prostatitis. [PDF]
Pathogenic bacteria cause chronic bacterial prostatitis (CBP). CPB is characterized by urinary tract infection and persistence of pathogenic bacteria in prostatic secretion.
Mohammad SI +7 more
europepmc +2 more sources
AbstractIn the dynamic landscape of pharmaceutical advancements, the strategic application of active pharmaceutical ingredients to the skin through topical and transdermal routes has emerged as a compelling avenue for therapeutic interventions. This non-invasive approach has garnered considerable attention in recent decades, with numerous attempts ...
Devika Nayak +2 more
exaly +3 more sources
A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo. [PDF]
ABSTRACT Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative stress, and neurogenic mechanisms.
Sallehuddin N +3 more
europepmc +2 more sources
Natural-based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications. [PDF]
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Omidian H, Akhzarmehr A, Bertol CD.
europepmc +2 more sources
Ultradeformable Vesicles: Concepts and Applications Relating to the Delivery of Skin Cosmetics
Skin aging is a phenomenon resulting in reduced self-confidence, thus becoming a major factor in social determinants of health. The use of active cosmetic ingredients can help prevent skin aging. Transfersomes are well known to be capable of deeply penetrating the dermis.
Andang Miatmoko +2 more
openaire +3 more sources
The Brazilian berry scientifically known as jabuticaba is a fruit covered by a dark purple peel that is still rich in bioactives, especially polyphenols.
Ines Castangia +5 more
doaj +1 more source
Ultradeformable Lipid Vesicles Localize Amphotericin B in the Dermis for the Treatment of Infectious Skin Diseases [PDF]
Cutaneous fungal and parasitic diseases remain challenging to treat, as available therapies are unable to permeate the skin barrier. Thus, treatment options rely on systemic therapy, which fail to produce high local drug concentrations but can lead to significant systemic toxicity.
Raquel Fernández-García +11 more
openaire +7 more sources
Transdermal immunization exhibits poor immunogenic responses due to poor permeability of antigens through the skin. Elastic liposomes, the ultradeformable nanoscale lipid vesicles, overcome the permeability issues and prove a versatile nanocarrier for ...
Ramesh Chaudhari +8 more
doaj +1 more source

