Host iron binding proteins acting as niche indicators for Neisseria meningitidis. [PDF]
PLoS ONE, 2009 Neisseria meningitidis requires iron, and in the absence of iron alters its gene expression to increase iron acquisition and to make the best use of the iron it has.
Philip W Jordan, Nigel J Saunders
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Antioxidants, 2023 We have previously demonstrated that the post-stroke administration of iron-free transferrin (apotransferrin, ATf) is beneficial in different models of ischemic stroke (IS) through the inhibition of the neuronal uptake of pro-oxidant iron. In the present
Alexia García-Serran +6 more
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Transferrin and Lactoferrin – Human Iron Sources for Enterococci [PDF]
Polish Journal of Microbiology, 2017 To overcome limitations in iron acquisition, enterococci have evolved a number of mechanisms to scavenge iron from the host iron-binding proteins – transferrin (TR) and lactoferrin (LF).
Paweł Lisiecki
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The expression of transferrin binding protein in the turtle nervous system
Archives of Histology and Cytology, 2009 Transferrin binding protein (TfBP) is a cytoplasmic glycoprotein that was originally isolated from the chick oviduct. As we previously demonstrated the constitutive expression of TfBP in the avian nervous system, in this study we examined whether TfBP is expressed in the reptilian nervous system.
Park, Sang Wook +5 more
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Antigenic and molecular heterogeneity of the transferrin-binding protein of Neisseria meningitidis [PDF]
FEMS Microbiology Letters, 1990 The transferrin-binding protein in 35 Neisseria meningitidis isolates was examined using a binding assay involving 125I-transferrin. The results show that most strains have a binding protein with a Mr between 78 kDa and 83 kDa; only 4 strains had a binding protein with a Mr of about 68 kDa.
E, Griffiths, P, Stevenson, A, Ray
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Transferrin-Binding Protein B of Neisseria meningitidis : Sequence-Based Identification of the Transferrin-Binding Site Confirmed by Site-Directed Mutagenesis [PDF]
Journal of Bacteriology, 2004 ABSTRACT A sequence-based prediction method was employed to identify three ligand-binding domains in transferrin-binding protein B (TbpB) of Neisseria meningitidis strain B16B6. Site-directed mutagenesis of residues located in these domains has led to the identification of two domains, amino acids 53 to 57
Renauld-Mongenie, G. +9 more
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Immunogenicity and antigenic heterogeneity of a human transferrin-binding protein in Neisseria meningitidis [PDF]
Infection and Immunity, 1992 Growing Neisseria meningitidis on an iron restriction medium induces the synthesis of new outer membrane proteins, some of them true iron-regulated outer membrane proteins (IROMPs) and others synthesized because of the stress produced by the iron restriction.
L, Ferron +3 more
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Gonococcal transferrin-binding protein 2 facilitates but is not essential for transferrin utilization [PDF]
Journal of Bacteriology, 1994 Pathogenic Neisseria species have been shown to scavenge iron from transferrin (Tf), although the mechanism is not yet fully understood. Two iron-repressible proteins that exhibit Tf-binding activity have been identified. This work describes the cloning and sequencing of tbpB, a 2.1-kb gene in N.
J E, Anderson +2 more
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Evaluation of Tc-99m (V) DMSA Binding to Human Plasma Proteins
Kaohsiung Journal of Medical Sciences, 2008 As a critical step toward elucidating the mechanism of localization of Tc-99m (V) dimercaptosuccinic acid (DMSA), we investigated its binding and transport in blood in comparison with Ga-67 citrate.
Bi-Fang Lee +6 more
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Characterisation of the meningococcal transferrin binding protein complex by photon correlation spectroscopy [PDF]
FEBS Letters, 1997 Photon correlation spectroscopy demonstrated for the first time that co‐purified meningococcal TbpA+B form a complex in solution. This structure bound hTf and the resultant species underwent partial dissociation after exposure to additional hTf or following prolonged incubation.
Boulton, I.C. +5 more
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