Results 51 to 60 of about 1,164,783 (293)

Iron homeostasis in full-term, normal birthweight Gambian neonates over the first week of life

Scientific Reports, 2023
Human neonates elicit a profound hypoferremia which may protect against bacterial sepsis. We examined the transience of this hypoferremia by measuring iron and its chaperone proteins, inflammatory and haematological parameters over the first post-partum ...
James H. Cross, Ousman Jarjou, Nuredin Ibrahim Mohammed, Santiago Rayment Gomez, Bubacarr J. B. Touray, Noah J. Kessler, Andrew M. Prentice, Carla Cerami   +7 more
doaj   +1 more source

α-Taxilin interacts with sorting nexin 4 and participates in the recycling pathway of transferrin receptor.

PLoS ONE, 2014
Membrane traffic plays a crucial role in delivering proteins and lipids to their intracellular destinations. We previously identified α-taxilin as a binding partner of the syntaxin family, which is involved in intracellular vesicle traffic.
Hiroshi Sakane, Yukimi Horii, Satoru Nogami, Yoji Kawano, Takako Kaneko-Kawano, Hiromichi Shirataki   +5 more
doaj   +1 more source

Quantitative analysis of the protein corona on FePt nanoparticles formed by transferrin binding [PDF]

Journal of The Royal Society Interface, 2009
Nanoparticles are finding a rapidly expanding range of applications in research and technology, finally entering our daily life in medical, cosmetic or food products. Their ability to invade all regions of an organism including cells and cellular organelles offers new strategies for medical diagnosis and therapy (nanomedicine), but their safe use ...
Nienhaus, G. U., Jiang, X., Weise, S., Hafner, M., Röcker, C., Zhang, F., Parak, W. J.   +6 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Determination of Surface-Exposed, Functional Domains of Gonococcal Transferrin-Binding Protein A [PDF]

Infection and Immunity, 2004
ABSTRACTThe gonococcal transferrin receptor is composed of two distinct proteins, TbpA and TbpB. TbpA is a member of the TonB-dependent family of integral outer membrane transporters, while TbpB is lipid modified and thought to be peripherally surface exposed.
Mary Kate, Yost-Daljev, Cynthia Nau, Cornelissen   +1 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells. [PDF]

PLoS ONE, 2017
Recycling endosomes are generally thought to play a central role in endocytic recycling, but recent evidence has indicated that they also participate in other cellular events, including cytokinesis, autophagy, and neurite outgrowth. Rab small GTPases are
Mai E Oguchi, Kenta Noguchi, Mitsunori Fukuda   +2 more
doaj   +1 more source

Urea Gel Electrophoresis in Studies of Conformational Changes of Transferrin on Binding and Transport of Non-Ferric Metal Ions

Gels, 2021
Transferrin (Tf) is a crucial transporter protein for Fe(III), but its biological role in binding other metal ions and their delivery into cells remain highly controversial.
Aviva Levina, Boer Wang, Peter A. Lay
doaj   +1 more source

Iron repressibility of siderophore and transferrin-binding protein inStaphylococcus aureus [PDF]

FEMS Microbiology Letters, 1998
In order to investigate whether the iron acquisition mechanisms of Staphylococcus aureus are induced by iron restriction in vitro, we examined S. aureus ATCC 6538 for production of siderophore and expression of transferrin-binding protein (SA-tbp) in normal or deferrated brain heart infusion broth (BHI).
Y, Lim, S H, Shin, S I, Lee, I S, Kim, J H, Rhee   +4 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source