Results 131 to 140 of about 212,698 (347)

Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury

open access: yesAdvanced Science, EarlyView.
ROS accumulation is an important upstream signal for activating transcellular autophagy. Incomplete autophagy and TNT formation are necessary conditions for activating transcellular autophagy, and the disruption of the autophagic fusion mechanism is a trigger for activating transcellular autophagy.
Tao Wang   +13 more
wiley   +1 more source

Serum transferrins in Merino sheep [PDF]

open access: gold, 1963
G. C. ASHTON, K. A. FERGUSON
openalex   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang   +9 more
wiley   +1 more source

Association of body iron stores and anemia in a Ghanaian type‐2 diabetes mellitus population: A multicentered cross‐sectional study

open access: yesHealth Science Reports
Background and Aims Anemia has been a common comorbidity in most chronic diseases, but has not been well monitored in type 2 diabetes mellitus (T2DM) patients.
Wina I. O. Boadu   +13 more
doaj   +1 more source

AuNP-Agglomerated monoliths in pipette tips for lectin affinity extraction of glycoproteins [PDF]

open access: yes, 2010
• To in situ fabricate ethylene dimethacrylate porous polymer monoliths within the confines of a commercial 20 μL polypropylene pipette tips. • To enhance the monolith surface area by immobilising AuNPs and then functionalise the AuNPs with ECL lectin
Alwael, Hassan   +5 more
core  

SERUM TRANSFERRIN POLYMORPHISM IN THE DEER MOUSE [PDF]

open access: bronze, 1966
David I. Rasmussen, Richard K. Koehn
openalex   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun   +14 more
wiley   +1 more source

Bimetallic Plasmonic Nanozyme‐Based Microneedle for Synergistic Ferroptosis Therapy of Melanoma

open access: yesAdvanced Science, EarlyView.
A microneedle (MN) patch that integrates novel bimetallic plasmonic nanozyme (BPNzyme) and traditional Chinese medicine β‐elemene (β‐ELE) has been rationally designed for ferroptosis pathway‐dependent combined therapy of melanoma. Abstract Melanoma is the most common malignant skin tumor, characterized by complexity, invasiveness, and heterogeneity ...
Wei Duan   +11 more
wiley   +1 more source

Transferrin Is Up-Regulated by Microbes and Acts as a Negative Regulator of Immunity to Induce Intestinal Immunotolerance

open access: yesResearch
Cross-talks (e.g., host-driven iron withdrawal and microbial iron uptake between host gastrointestinal tract and commensal microbes) regulate immunotolerance and intestinal homeostasis.
Xiaopeng Tang   +16 more
doaj   +1 more source

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