Results 11 to 20 of about 2,476,356 (396)

Transferrin Receptor [PDF]

Definitions, 2020
C. Enns, E. Rutledge, A. Williams
semanticscholar   +3 more sources

Transferrin receptor targeting chimeras for membrane protein degradation. [PDF]

Nature
Zhang D, Duque-Jimenez J, Facchinetti F, Brixi G, Rhee K, Feng WW, Jänne PA, Zhou X.   +7 more
europepmc   +2 more sources

Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents

Frontiers in Immunology, 2021
The transferrin receptor 1 (TfR1), also known as cluster of differentiation 71 (CD71), is a type II transmembrane glycoprotein that binds transferrin (Tf) and performs a critical role in cellular iron uptake through the interaction with iron-bound Tf ...
Pierre V Candelaria, L. Leoh, M. Penichet, T. R. Daniels-Wells   +3 more
semanticscholar   +1 more source

Transferrin Receptor-Targeted Nanocarriers: Overcoming Barriers to Treat Glioblastoma

Pharmaceutics, 2022
Glioblastoma multiforme (GBM) is the most common and lethal type of brain tumor, and the clinically available approaches for its treatment are not curative.
M. J. Ramalho, J. Loureiro, M. Coelho, M. C. Pereira   +3 more
semanticscholar   +1 more source

Investigation of Trends in the Research on Transferrin Receptor-Mediated Drug Delivery via a Bibliometric and Thematic Analysis

Pharmaceutics, 2022
This study systematically reviews and characterizes the existing literature on transferrin/transferrin receptor-mediated drug delivery. Transferrin is an iron-binding protein. It can be used as a ligand to deliver various proteins, genes, ions, and drugs
Tarnjot Kaur, Jyoti Upadhyay, Sudeep Pukale, Ashish Mathur, Mohd Nazam Ansari   +4 more
doaj   +1 more source

Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

Journal of Cachexia, Sarcopenia and Muscle, 2021
Satellite cells (SCs) are critical to skeletal muscle regeneration. Inactivation of SCs is linked to skeletal muscle loss. Transferrin receptor 1 (Tfr1) is associated with muscular dysfunction as muscle‐specific deletion of Tfr1 results in growth ...
Hongrong Ding, Shujie Chen, Xiaohan Pan, Xiaoshuang Dai, Guihua Pan, Ze Li, Xudong Mai, Ye Tian, Susu Zhang, Bingdong Liu, Guangchao Cao, Zhicheng Yao, Xiangping Yao, Liang Gao, Li Yang, Xiaoyan Chen, Jia Sun, Hong Chen, Mulan Han, Yulong Yin, Guohuan Xu, Huijun Li, Weidong Wu, Zheng Chen, Jingchao Lin, Liping Xiang, Jun Hu, Yan Lu, Xiao Zhu, Liwei Xie   +29 more
semanticscholar   +1 more source

Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome c via a transferrin conjugate. [PDF]

PLoS ONE, 2018
One of the major drawbacks of many of the currently used cancer drugs are off-target effects. Targeted delivery is one method to minimize such unwanted and detrimental events.
Manoj Saxena, Yamixa Delgado, Rohit Kumar Sharma, Shweta Sharma, Solimar Liz Ponce De León Guzmán, Arthur D Tinoco, Kai Griebenow   +6 more
doaj   +1 more source

A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies. [PDF]

Elife
Balligand T, Carpenet C, Olivé Palau S, Jaspers T, Suresh P, Liu X, Medhi H, Lee YH, Rashidian M, De Strooper B, Ploegh HL, Dewilde M.   +11 more
europepmc   +3 more sources

Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme

bioRxiv, 2021
Delivery of biotherapeutics across the blood-brain barrier (BBB) is a challenge. Many approaches fuse biotherapeutics to platforms that bind the transferrin receptor (TfR), a brain endothelial cell target, to facilitate receptor-mediated transcytosis ...
A. Arguello, Cathal S. Mahon, M. E. Calvert, D. Chan, J. Dugas, Michelle E. Pizzo, Elliot R. Thomsen, Roni Chau, Lorna A Damo, Joseph Duque, Meng Fang, T. Giese, Do Jin Kim, Nicholas Liang, Hoang N. Nguyen, Hilda Solanoy, Buyankhishig Tsogtbaatar, J. Ullman, Junhua Wang, M. Dennis, D. Diaz, K. Gunasekaran, K. Henne, Joseph W. Lewcock, P. Sanchez, M. Troyer, Jeffrey M Harris, K. Scearce-Levie, L. Shan, R. Watts, R. Thorne, Anastasia G. Henry, Mihalis S. Kariolis   +32 more
semanticscholar   +1 more source

RELATIONSHIP OF CHANGES IN HEMATOLOGICAL AND BIOCHEMICAL INDICATORS OF PERIPHERAL BLOOD WITH THE TRANSFERRIN CONCENTRATION AND CD71+ LYMPHOCYTE COUNT

Siberian Journal of Life Sciences and Agriculture, 2022
Transferrin is an essential component of cell growth and metabolic processes that require iron. An increase in the expression of transferrin receptors on lymphocytes ensures their differentiation, maturation and activation of proliferation.
Veronika V. Patrakeeva, Liliya K. Dobrodeeva, Natal’ya P. Geshavec   +2 more
doaj   +1 more source