Results 71 to 80 of about 28,814 (279)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis and Critique of the Theory of Transformational Leadership [PDF]

open access: yesاسلام و مدیریت
Transformational leadership occurs when the leader and the follower lead each other to higher levels of values and motivations. This is the product of mutual transformational influence of leaders and followers.
doaj  

Investigating the Impact of Transformational School Leadership: Teacher Perceptions and the Role of Leadership Training Programs

open access: yesEducation Sciences
This study was driven by two primary objectives. The first objective focused on exploring the relationship between transformational and transactional leadership practices and teachers’ perceptions of their principals’ effectiveness.
Prokopis Constantinou   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

The Influence of Leadership, Talent Management, Organizational Cultureand Organizational Support on Employee Engagement

open access: yesInternational Research Journal of Business Studies, 2012
A leadership-driven model was hypothesized to examine the simultaneous influences of three dimensions of leadership behaviors (transformational, transactional, and interaction between transformational and transactional) on employee engagement, mediated ...
Jimmy Sadeli
doaj  

Back to Basics: The Relative Importance of Transformational and Fair Leadership for Employee Work Engagement and Exhaustion

open access: yesScandinavian Journal of Work and Organizational Psychology, 2016
This study contributes to the literature on the supervisors’ role in employee well-being by drawing on two separate lines of research: transformational leadership and organizational justice.
Kaisa Perko   +3 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

The Transformational Leadership in a Public Educational Institution

open access: yesEducación, 2014
The transformational leadership allows managers influence their teachers who recognize and attributed control to the director. The research investigated what are the characteristics of the transformational leadership of the director of a public ...
Ysrael Alberto Martínez Contreras
doaj  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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