Results 71 to 80 of about 1,364,752 (208)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

From farmer to entrepreneur: transformative learning in the making of a new professional identity in EU agricultural workers. A case study

, 2011
The case study refers to the outcomes of the UE Leonardo project TAS for Agriform addressed to a specific target of adult learners: agricultural farmers, over 50, who are compelled to become entrepreneurs in order to cope with the new market trends and ...
STRIANO, MAURA
core  

Teacher agency during a K-12 place-based collaborative design process centered around a socio-scientific issue in Northern Alaska

Disciplinary and Interdisciplinary Science Education Research
In the face of pressing socio-scientific issues and the underrepresentation of Indigenous and marginalized students in STEM, there is an increasing need to integrate socio-scientific issues into the classroom through transformative pedagogical approaches.
Solaire Finkenstaedt-Quinn, Archer Harrold, Megan Gibas, Avery Long, Ginger Shultz   +4 more
doaj   +1 more source

New Perspectives on Collective Collaboration Within and Between Change Laboratory Sessions

Education Sciences
This article contributes new knowledge on collaboration within and between Change Laboratory sessions and how it offers the potential to support the zone of proximal development and the expansive learning of participants.
Camilla Finsterbach Kaup, Susanne Dau
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Central 6 Definitions

, 2019
The University of Central Oklahoma adopted, by 2009, Central 6 Tenets of Transformative Learning. These are core areas in which the university is committed to providing its students with transformative growth. This document provides the short definitions
UCO Student Transformative Learning Record
core  

Transformative Learning for Knowledge: From Meaning Perspectives to Threshold Concepts [PDF]

, 2018
Mainstream transformative learning emphasizes personally significant learning and liberation from limited ways of being in the world. Reflecting humanistic and emancipatory philosophical commitments, this emphasis can make it difficult to appreciate the ...
Hodge, Steven, Steven Hodge
core   +1 more source

Beyond Discourse: Notes on Spatial Agency

Footprint, 2009
This article investigates the word ‘agency’ in relation to the role, responsibility and power of the architect. Using Anthony Giddens’s formulation of agency, we discuss the transformative potential of architecture where the lack of a predetermined ...
Tatjana Schneider, Jeremy Till
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Towards Multilayered Framework Of Digital Agency: Insights From A Rapid Hybrid Review

Digital Culture & Education
Digital agency is an emerging concept in research on technology use in education, socialinclusion, and working life, yet its conceptual fragmentation calls for synthesis.
Paulina Rikala, Minna Ylönen, Panu Forsman, Susanna Paloniemi, Tommi Kärkkäinen, Raija Hämäläinen   +5 more
doaj