Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. [PDF]
The in vitro process of chondrogenic differentiation of mesenchymal stem cells for tissue engineering has been shown to require three-dimensional culture along with the addition of differentiation factors to the culture medium.
Rune B Jakobsen +4 more
doaj +1 more source
Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
Background Nerve growth factor (NGF) contributes to pain in knee osteoarthritis (KOA) patients. Transforming growth factor-beta (TGF-β) stimulates NGF expression in chondrocytes from KOA patients.
Shotaro Takano +10 more
doaj +1 more source
Kadar Kortisol, Transforming Growth Factor β, serta Derajat Adhesi Pasca Laparoskopi dan Laparotomi
Adhesi intraperitoneal pasca bedah abdomen terjadi pada 50-97% kasus adhesi, dengan penyebab terbanyak adalah laparotomi. Penelitian ini bertujuan membuktikan perbedaan dampak laparoskopi dan laparotomi terhadap derajat adhesi peritoneal, kadar kortisol dan TGF-β.
Agung Pribadi +2 more
openaire +1 more source
Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients
The pathophysiology of human keratoconus (KC), a bilateral progressive corneal disease leading to protrusion of the cornea, stromal thinning, and scarring, is not well-understood.
Hui Qi +7 more
doaj +1 more source
ABSTRAKSel monosit merupakan target utama infeksi virus Demam Berdarah Dengue (DBD) yang dapat memproduksi faktor vasoaktif yang mempengaruhi fungsi sel endotel dan berperan dalam kebocoran vaskuler. Transforming growth factor beta 1 (TGF-1) merupakan salah satu sitokin yang mempunyai banyak peran dalam patogenesis DBD.
Mohamad Supriatna +4 more
openaire +1 more source
The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-β1âstimulated wound contraction [PDF]
Dermal fibrosis, or scarring, following surgical incisions, traumatic wounds and burns presents a major clinical burden. Transforming growth factor (TGF)-beta1 is a major factor known to stimulate fibroblast proliferation, collagen production, and the differentiation of fibroblast to myofibroblast promoting wound contraction.
Benjamin R, Klass +3 more
openaire +2 more sources
DETEKSI KADAR TRANSFORMING GROWTH FACTOR (TGF-β) PADA LUKA AKUT
Highlights: • Peningkatan kadar TGF-β dalam fase proliferasi luka dapat berperan dalam stimulasi fibroblas untuk menghasilkan lebih banyak kolagen dalam pembentukan jaringan parut.
Pratidina Wulandari +2 more
doaj +1 more source
Low Transforming Growth Factor-β Pathway Activity in Cervical Adenocarcinomas
Cervical cancer is the fourth most common cancer in women worldwide. Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are the most common histological types, with AC patients having worse prognosis.
Dieuwke L. Marvin +11 more
doaj +1 more source
Vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β1) play an important role in angiogenesis. We wanted to determine if concentrations of growth factors in the coronary sinus (CS) and right atrium (RA) are higher in coronary
Tsung-Hsien Lin +7 more
doaj +1 more source
Transforming growth factor-β: Biology and application to cancer therapy [PDF]
Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis.
Ivanović Vesna
doaj +1 more source

