Results 31 to 40 of about 234,812 (200)

Transforming Growth Factor-α Attenuates N-Methyl-D-aspartic Acid Toxicity in Cortical Cultures by Preventing Protein Synthesis Inhibition through an Erk1/2-dependent Mechanism [PDF]

Journal of Biological Chemistry, 2003
Transforming growth factor-alpha (TGF-alpha), a ligand of the epidermal growth factor receptor, reduces the infarct size after focal cerebral ischemia in rat, but the molecular basis underlying the protection is unknown. Excitotoxicity and global inhibition of translation are acknowledged to contribute significantly to the ischemic damage.
Petegnief, Valérie, Friguls, Bibiana, Sanfeliu, Coral, Suñol, Cristina, Planas, Anna M.   +4 more
openaire   +3 more sources

Type-1 Collagen differentially alters β-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells

BMC Musculoskeletal Disorders, 2009
Background Dupuytren's Disease (DD) is a debilitating contractile fibrosis of the palmar fascia characterised by excess collagen deposition, contractile myofibroblast development, increased Transforming Growth Factor-β levels and β-catenin accumulation ...
Gan Bing, Wu Yan, Njarlangattil Anna, Vi Linda, O'Gorman David B   +4 more
doaj   +1 more source

Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough

Respiratory Research, 2009
In patients with chronic idiopathic cough, there is a chronic inflammatory response together with evidence of airway wall remodelling and an increase in airway epithelial nerves expressing TRPV-1.
Lee Kang-Yun, Nassenstein Christina, Hew Mark, Macedo Patricia, Xie Shaoping, Chung Kian   +5 more
doaj   +1 more source

Transforming growth factor-β: A therapeutic target for cancer

Human Vaccines & Immunotherapeutics, 2017
Transforming growth factor-β (TGF-β) regulates cell growth and differentiation, apoptosis, cell motility, extracellular matrix production, angiogenesis, and cellular immunity. It has a paradoxical role in cancer.
Sulsal Haque, John C. Morris
doaj   +1 more source

Effects of the administration of pentoxifylline and prednisolone on the evolution of portal fibrogenesis secondary to biliary obstruction in growing animals: immunohistochemical analysis of the expression of TGF-β and VEGF

Clinics, 2012
OBJECTIVE: During the neonatal and infancy periods, some chronic liver diseases may lead to progressive hepatic fibrosis, which is a condition that can ultimately result in the loss of organ function and severe portal hypertension necessitating hepatic ...
Wagner de Castro Andrade, Luiz Fernando Ferraz da Silva, Maria Cecilia de Mendonça Coelho, Ana Cristina Aoun Tannuri, Venancio Avancini Ferreira Alves, Uenis Tannuri   +5 more
doaj   +1 more source

Peran transforming growth factor-`β pada reaksi eritema nodosum leprosum berulang

Media Dermato-Venereologica Indonesiana, 2019
Eritema nodosum leprosum (ENL) berulang adalah suatu komplikasi imunologi Kusta yang serius, menyebabkan peradangan pada kulit, saraf dan organ lain yang menyebabkan penurunan kualitas hidup pasien. Tujuan penelitian ini adalah untuk menelaah hubungan Transforming Growth Factor-β (TGF-β) dengan ENL berulang pada pasien kusta. Metode desain penelitian
openaire   +2 more sources

Dual‐Specificity Phosphatase 26 Protects Against Cardiac Hypertrophy Through TAK1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Heart pathological hypertrophy has been recognized as a predisposing risk factor for heart failure and arrhythmia. DUSP (dual‐specificity phosphatase) 26 is a member of the DUSP family of proteins, which has a significant effect on ...
Jing Zhao, Xiaoli Jiang, Jinhua Liu, Ping Ye, Lang Jiang, Manhua Chen, Jiahong Xia   +6 more
doaj   +1 more source

Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss

Frontiers in Aging Neuroscience, 2015
Unfortunately, the second author affiliation in the originally published article was incorrectly stated as being “Centre for Biomedical Network Research (CIBER), Institute of Health Carlos III (ISCIII), Madrid, Spain.” The correct author's affiliation is “Centre for Biomedical Network Research on Rare Diseases (CIBERER), Institute of Health Carlos ...
Silvia eMurillo-Cuesta, Silvia eMurillo-Cuesta, Silvia eMurillo-Cuesta, Lourdes eRodríguez-de La Rosa, Lourdes eRodríguez-de La Rosa, Lourdes eRodríguez-de La Rosa, Julio eContreras, Julio eContreras, Julio eContreras, Adelaida M Celaya, Adelaida M Celaya, Guadalupe eCamarero, Guadalupe eCamarero, Guadalupe eCamarero, Teresa eRivera, Teresa eRivera, Teresa eRivera, Isabel eVarela-Nieto, Isabel eVarela-Nieto, Isabel eVarela-Nieto   +19 more
openaire   +4 more sources

THE ROLE OF CYTOKINES AND AGMATINE IN THE DEVELOPING PLACENTA WITH PHYSIOLOGICAL AND PREGNANCY COMPLICATED

Медицинский вестник Юга России, 2013
Purpose: To study the content of cytokines and agmatine in the development of the placenta in physiological and complicated gestation.Materials and Methods: 57 women, of which 34 women with physiological pregnancy and 23 women with placental ...
A. S. Degtyareva, I. I. Krukier, E. V. Narezhnaya, V. V. Avrutskaya, M. A. Levkovich, A. A. Nikashina   +5 more
doaj   +1 more source

Prognostic value of matrix metalloproteinases and transforming growth factor – β in kidney cancer

Исследования и практика в медицине, 2022
Purpose of the study. The study's objective is to investigate the expression level of tissue and serum markers of oncogenesis and nephrofibrosis transforming growth factor beta (TGF‑β) and matrix metalloproteinase‑9 (MMP‑9) in patients operated for ...
A. I. Tarasenko, A. N. Rossolovskiy, O. L. Berezinets, A. B. Bucharskaya, S. S. Pakhomiy, A. O. Efimova, G. N. Maslyakova   +6 more
doaj   +1 more source