Results 131 to 140 of about 13,909 (173)

Urinary transforming growth factor beta1 in children and adolescents with congenital solitary kidney

Pediatric Nephrology, 2009
The aim of the study was to assess urinary transforming growth factor beta1 (TGF beta1) level in children and adolescents with congenital solitary kidney (CSK), depending on estimated glomerular filtration rate (eGFR) and compensatory overgrowth of the kidney. The study group (I) consisted of 65 children and young adults, 0.5-22 years of age (median 10.
Katarzyna Taranta-Janusz, , Walentyna Zoch-Zwierz   +2 more
exaly   +3 more sources

Transforming growth factor-beta1 inhibits thrombin activation of endothelial cells

Cytokine, 2004
Transforming growth factor-beta1 (TGF-beta1) is reported to exert both pro- and anti-inflammatory effects on the chronic activation of endothelial cells (ECs) in vitro by cytokines such as tumour necrosis factor-alpha (TNF-alpha). However, the effects of TGF-beta1 on acute inflammatory responses of ECs in vitro (e.g.
Harriet, Harris, Heide, Kirschenlohr, Nicole, Szabados, James, Metcalfe   +3 more
openaire   +2 more sources

Tissue Localization of Transforming Growth Factor-Beta1 in Pulmonary Eosinophilic Granuloma

American journal of respiratory and critical care medicine, 1996
Abstract Pulmonary eosinophilic granuloma is characterized by infiltration of the lungs with fibronodular lesions containing specialized Langerhans' cells. In some patients, progressive pulmonary fibrosis leads to significant respiratory impairment.
S, Asakura, T V, Colby, A H, Limper
openaire   +2 more sources

Transforming growth factor-beta1 in hemangioma of the ovary.

Gynecologic and obstetric investigation, 1998
Hemangioma of the ovary is extremely rare. We report the case of a 32-year-old woman who complained of pelvic pain due to a large right adnexal mass. On surgical exploration a 10 x 8 cm hemangioma of the ovary was resected. Expression of transforming growth factor-beta1 was studied, and the possible role of this molecule in the development of the tumor
Loverro G, Cormio G, Perlino E, Vicino M, Cazzolla A, Selvaggi L   +5 more
openaire   +4 more sources

Transforming Growth Factor-β1 and Disorders of the Lung

Cell Biochemistry and Biophysics, 2005
The transforming growth factor (TGF) superfamily encompasses about 30 members in mammals. The effect of TGF-beta subfamily members is exerted and regulated via selective pathways of synthesis and signaling that involve activation of latent TGF-beta, specific and high-affinity binding to cell membrane serine/threonine kinase receptors, activation of ...
Blanca, Camoretti-Mercado, Julian, Solway   +1 more
openaire   +2 more sources

Transforming Growth Factor-ß1 and Prostate Cancer

Scandinavian Journal of Urology and Nephrology, 2000
Transforming growth factor-beta1 (TGF-beta1) is an important regulator of the normal and malignant prostate. In the non-malignant prostate, TGF-beta1 stimulates cell differentiation, inhibits epithelial cell proliferation and induces epithelial cell death. TGF-beta1 is secreted into semen and here it is an important immunosuppressive factor.
P, Wikström, A, Bergh, J E, Damber
openaire   +2 more sources

Transforming growth factor-beta1 and lung allograft fibrosis.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1998
Transforming growth factor beta1 (TGF-beta1) is a potent immunosuppressive cytokine that promotes fibrosis by enhancing the synthesis of extracellular matrix components. The repair process following lung allograft injury is due to rejection or infection replaces lung parenchyma by fibrotic tissue, leading to pulmonary dysfunction. The role of TGF-beta1
El-Gamel, A, Awad, M, Sim, E, Hasleton, P, Egan, J, Yonan, NN A, Deiraniya, A, Hutchinson, I.   +7 more
openaire   +2 more sources

Mandibular Reconstruction With Transforming Growth Factor‐β1

The Laryngoscope, 1998
AbstractHypothesis: Transforming growth factor‐β1 (TGF‐β1) plus demineralized bone matrix (DBM) will reconstruct a critical mandibular defect devoid of periosteum in a canine model.Study Design: Randomized, blinded, placebo‐controlled, prospective animal pilot study.Methods: Canine critical mandibular defects devoid of periosteum were reconstructed ...
D A, Sherris, C S, Murakami, W F, Larrabee, A G, Bruce   +3 more
openaire   +2 more sources

Regulation of transforming growth factor beta1 by nitric oxide.

Cancer research, 1999
Many tumor cells or their secreted products suppress the function of tumor-infiltrating macrophages. Tumor cells often produce abundant transforming growth factor beta1 (TGF-beta1), which in addition to other immunosuppressive actions suppresses the inducible isoform of NO synthase.
Y, Vodovotz, L, Chesler, H, Chong, S J, Kim, J T, Simpson, W, DeGraff, G W, Cox, A B, Roberts, D A, Wink, M H, Barcellos-Hoff   +9 more
openaire   +1 more source

[The mechanism of transforming growth factor beta1 in myofibroblast differentiation].

Zhonghua wai ke za zhi [Chinese journal of surgery], 2008
To investigate the mechanism underlying myofibroblast differentiation induced by transforming growth factor (TGF) beta1 in obliterative bronchiolitis following lung transplantation.Heterotopic tracheal transplantation was performed in Smad3 wild-type and knock-out mice to simulate the lung transplantation in human.
Hong-xu, Liu, Si-wen, Wang, Cheng-hai, Zhao, Yang, Liu, Yu, Li, Qi-gang, Zhang, Wei, Cong, Xin-gang, Lan, Shun, Xu, Li-bo, Han, Lin, Zhang   +10 more
openaire   +1 more source