Results 151 to 160 of about 9,205,124 (201)
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Suppression of Transforming Growth Factor-beta1 Expression in Keloids After Cryosurgery
Cryobiology, 2017The biological mechanism underlying cryosurgical treatment of keloids remains unclear. Transforming growth factor-beta1 (TGF-β1) has been implicated in the pathogenesis of keloids and was reported to be the target of several therapeutic modalities. However, the effect of cryosurgery on its expression in keloid tissue has not been yet investigated.
Rania Makboul, Abeer Refaiy, Sara M Awad
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Expression of Transforming Growth Factor β1 in Ameloblastomas
Journal of Craniofacial Surgery, 2008The aim of the present study was to compare the expression of transforming growth factor (TGF) beta1 in ameloblastomas (AMs) with different risk of recurrence by immunohistochemistry. A total of 29 cases of AMs were evaluated. The tumors were divided into 2 groups: group A (10 cases) composed of unicystic and peripheral AMs, associated with a low risk ...
IEZZI, GIOVANNA +6 more
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Transforming growth factor-beta1 and regulators of apoptosis.
Annals of the New York Academy of Sciences, 2009Growth inhibitory function of transforming growth factor-beta1 (TGF-beta1) is abolished in colorectal cancer cells as a consequence of mutations of various downstream signaling agents, such as p53, which fail to respond to TGF-beta1 stimulation. TGF-beta1 could also suppress T-cell-mediated anticancer immunity.
Stanislaw, Sulkowski +3 more
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The role of transforming growth factor β1 in the vascular system
Cardiovascular Pathology, 2005The transforming growth factor beta (TGFbeta) family of cytokines exert pleiotropic effects upon a wide variety of cell types. TGFbeta1 has been demonstrated to be of fundamental importance in the development, physiology and pathology of the vascular system.
Ghosh, J +6 more
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Transforming Growth Factor β1: Implications in Adrenocortical Tumorigenesis
Endocrine Research, 2000TGFbeta1, a multifunctional growth modulator, inhibits the proliferation of epithelial cells. TGFbeta1 signaling is dependent on the heterodimerization of the TGFbeta1 receptor II (TGFbeta1RII) with the TGFbeta1 receptor I (TGFbeta1RI). The cytoplasmic proteins Smads are the mediators of the TGFbeta1 signal.
ARNALDI G. +4 more
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Transforming growth factor-beta1 inhibits thrombin activation of endothelial cells
Cytokine, 2004Transforming growth factor-beta1 (TGF-beta1) is reported to exert both pro- and anti-inflammatory effects on the chronic activation of endothelial cells (ECs) in vitro by cytokines such as tumour necrosis factor-alpha (TNF-alpha). However, the effects of TGF-beta1 on acute inflammatory responses of ECs in vitro (e.g.
Harriet, Harris +3 more
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Urinary Transforming Growth Factor beta1 in Children and Adolescents With Congenital Solitary Kidney
Pediatric Nephrology, 2009The aim of the study was to assess urinary transforming growth factor beta1 (TGF beta1) level in children and adolescents with congenital solitary kidney (CSK), depending on estimated glomerular filtration rate (eGFR) and compensatory overgrowth of the kidney. The study group (I) consisted of 65 children and young adults, 0.5-22 years of age (median 10.
Katarzyna Taranta-Janusz
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Transforming growth factor-beta1 inhibits steroidogenesis in human trophoblast cells
Molecular Human Reproduction, 2002Transforming growth factor-beta (TGF-beta) is an important regulator of placental development and function. In this study, we have investigated the effect of TGF-beta1 on steroidogenesis, as well as its sites of action in the steroidogenic pathway by using a choriocarcinoma cell line, JEG-3, and a normal trophoblast cell line (NPC).
Shuang, Luo +3 more
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Tissue Localization of Transforming Growth Factor-Beta1 in Pulmonary Eosinophilic Granuloma
American journal of respiratory and critical care medicine, 1996Abstract Pulmonary eosinophilic granuloma is characterized by infiltration of the lungs with fibronodular lesions containing specialized Langerhans' cells. In some patients, progressive pulmonary fibrosis leads to significant respiratory impairment.
S, Asakura, T V, Colby, A H, Limper
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Mandibular Reconstruction With Transforming Growth Factor‐β1
The Laryngoscope, 1998AbstractHypothesis: Transforming growth factor‐β1 (TGF‐β1) plus demineralized bone matrix (DBM) will reconstruct a critical mandibular defect devoid of periosteum in a canine model.Study Design: Randomized, blinded, placebo‐controlled, prospective animal pilot study.Methods: Canine critical mandibular defects devoid of periosteum were reconstructed ...
D A, Sherris +3 more
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