Results 11 to 20 of about 13,909 (173)

Transforming growth factor beta1 and aldosterone. [PDF]

Curr Opin Nephrol Hypertens, 2015
It is well established that blocking renin-angiotensin II-aldosterone system (RAAS) is effective for the treatment of cardiovascular and renal complications in hypertension and diabetes mellitus. Although the induction of transforming growth factor beta1 (TGFbeta1) by components of RAAS mediates the hypertrophic and fibrogenic changes in cardiovascular-
Matsuki K, Hathaway CK, Chang AS, Smithies O, Kakoki M.   +4 more
europepmc   +4 more sources

Increased transforming growth factor-beta1 in alcohol dependence. [PDF]

J Korean Med Sci, 2009
Ethanol and its metabolite acetaldehyde increase transforming growth factor beta1 (TGF-beta1) expression in animal studies. TGF-beta1 is related with the hepatic stellate cell (the key element of hepatic fibrogenesis) and the radial glia (the key element of neuronal migration).
Kim YK, Lee BC, Ham BJ, Yang BH, Roh S, Choi J, Kang TC, Chai YG, Choi IG.   +8 more
europepmc   +3 more sources

Transforming growth factor-beta1 in sarcoidosis [PDF]

European Respiratory Journal, 1998
Transforming growth factor-beta (TGF-beta) is a cytokine that promotes extracellular matrix accumulation and inhibits matrix degradation. Although the natural course of sarcoidosis is usually favourable, granuloma healing in the lung may result in pulmonary fibrosis and respiratory impairment in some patients.
F, Salez, P, Gosset, M C, Copin, C, Lamblin Degros, A B, Tonnel, B, Wallaert   +5 more
openaire   +2 more sources

TGF-β1 on induced osteogenic differentiation of human dermal fibroblast [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE: To evaluate the role of transforming growth factor beta 1 (TGF-β1) on the induced osteogenic differentiation of human dermal fibroblasts. METHODS: We performed four groups with cultured dermal fibroblasts according to the culture medium: CONTROL
Antonio Carlos Aloise, Max Domingues Pereira, Silvio Eduardo Duailibi, Alfredo Gragnani, Lydia Masako Ferreira   +4 more
doaj   +1 more source

Resveratrol downregulates TGF-β1 and Smad3 expression and attenuates oxidative stress in CCl4-induced kidney damage in rats

Asian Pacific Journal of Tropical Biomedicine, 2020
Objective: To evaluate the effect of resveratrol against CCl4- induced nephrotoxicity. Methods: Forty-two male Wistar rats were divided into seven groups randomly.
Saeed Mohammadi, Jamshid Karimi, Heidar Tavilani, Iraj Khodadadi, Roohollah Mohseni, Mohammad Hashemnia   +5 more
doaj   +1 more source

Transforming growth factor beta1 (TGF-ß1) levels in a rat model of induced pleural empyema [PDF]

Acta Cirúrgica Brasileira, 2018
Purpose: To evaluate the concentration of transforming growth factor beta 1 (TGFB1) levels in a rat pleural effusion obtained by inoculation of intrapleural bacteria or turpentine through thoracentesis.
Samanta Sarmento da Silva, Guilherme Eckert Peterson, Sérgio Luis Amantéa, Patrícia Miorelli, Jane Maria Ulbrich, Eliane Roesch, Paulo Roberto Sanches, Jose Carlos Fraga   +7 more
doaj   +1 more source

The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice. [PDF]

Proceedings of the National Academy of Sciences, 1996
All three isoforms of transforming growth factors beta (TGF-betal, TGF-beta2, and TGF-beta3) are secreted as latent complexes and activated extracellularly, leading to the release of the mature cytokines from their noncovalently associated proregions, also known as latency-associated peptides (LAPs).
E P, Böttinger, V M, Factor, M L, Tsang, J A, Weatherbee, J B, Kopp, S W, Qian, L M, Wakefield, A B, Roberts, S S, Thorgeirsson, M B, Sporn   +9 more
openaire   +2 more sources

Role of TGF-beta1 and MAP kinases in the antiproliferative effect of aspirin in human vascular smooth muscle cells. [PDF]

PLoS ONE, 2010
We aimed to test the antiproliferative effect of acetylsalicylic acid (ASA) on vascular smooth muscle cells (VSMC) from bypass surgery patients and the role of transforming growth factor beta 1 (TGF-beta1).VSMC were isolated from remaining internal ...
Santiago Redondo, Emilio Ruiz, Antonio Gordillo-Moscoso, Jorge Navarro-Dorado, Marta Ramajo, Manuel Carnero, Fernando Reguillo, Enrique Rodriguez, Teresa Tejerina   +8 more
doaj   +1 more source

Differential Expression of miR-21-5p, miR-20a-5p, TGF-β1, and TGF-β Receptor 2 in Skin, Serum, and Lung Samples Exposed to Sulfur Mustard

Iranian Journal of Allergy, Asthma and Immunology, 2023
Sulfur mustard (SM) or mustard gas is a blister chemical agent that causes pulmonary damage by triggering inflammation and oxidative injury. Alterations in microRNA (miR) transcript levels are found in pulmonary diseases and even inflammation. Therefore,
Mohadeseh Valizadeh, Shiva Irani, Mahmood Tavallaei, Masoud Soleimani   +3 more
doaj   +1 more source

Transforming growth factor beta-1 and vascular endothelial growth factor in the recovery and formation of skin scars

RUDN Journal of Medicine, 2021
Relevance. Scars are multi-tissue structures that significantly reduce the quality of life of the young, able-bodied population. The most socially significant variants are represented by hypertrophic and keloid postoperative scars and scars after burns ...
Varvara G. Nikonorova, Vladimir V. Chrishtop, Tatyana A. Rumyantseva   +2 more
doaj   +1 more source