Results 31 to 40 of about 9,205,124 (201)

Arrest of endotoxin-induced hypotension by transforming growth factor beta1. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1996
Septic shock is a cytokine-mediated process typically caused by a severe underlying infection. Toxins generated by the infecting organism trigger a cascade of events leading to hypotension, to multiple organ system failure, and frequently to death. Beyond supportive care, no effective therapy is available for the treatment of septic shock. Nitric oxide
M A, Perrella   +10 more
openaire   +2 more sources

Shen-Kang protects against tacrolimus-induced renal injury [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a rat model of chronic tacrolimus ...
Long Ye Zhang   +9 more
doaj   +1 more source

Suppression of keratinocyte growth and differentiation by transforming growth factor beta 1 involves multiple signaling pathways

open access: yes, 2001
Transforming growth factor beta1 treatment of keratinocytes results in a suppression of differentiation, an induction of extracellular matrix production, and a suppression of growth.
Cavanagh, Lois L.   +2 more
core   +1 more source

Effect of EDTA on TGF-β1 released from the dentin matrix and its influence on dental pulp stem cell migration

open access: yesBrazilian Oral Research
: Bioactive molecules stored in dentin, such as transforming growth factor beta1 (TGF-b1), may be involved in the signaling events related to dental tissue repair.
Lidiany Freitas GONÇALVES   +7 more
doaj   +1 more source

Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis

open access: yes, 2007
Recent studies have shown that myostatin, first identified as a negative regulator of skeletal muscle growth, may also be involved in the formation of fibrosis within skeletal muscle.
Huard, Johnny   +8 more
core   +1 more source

Low-dose interleukin-2 reverses chronic migraine-related sensitizations through peripheral interleukin-10 and transforming growth factor beta-1 signaling

open access: yesNeurobiology of Pain, 2022
Low-dose interleukin-2 (LD-IL-2) treatment has been shown to effectively reverse chronic migraine-related behaviors and the sensitization of trigeminal ganglion (TG) neurons through expansion and activation of peripheral regulatory T cells (Tregs) in ...
Zhaohua Guo   +5 more
doaj   +1 more source

Irisin Regulates the Functions of Hepatic Stellate Cells [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility which are characteristics of liver fibrogenesis.
Hanh Nguyen Dong   +4 more
doaj   +1 more source

Transforming growth factor beta1 up-regulates interferon regulatory factor 8 during dendritic cell development

open access: yes, 2007
Langerhans cells (LC) represent the cutaneous contingent of dendritic cells (DC). Their development critically depends on transforming growth factor beta1 (TGF-beta1) as demonstrated by analysis of TGF-beta1(-/-) mice, which lack LC.
Bartz, C.   +29 more
core   +1 more source

Retrieval‐Based Deep Hybrid Models for Robust Network Intrusion Detection

open access: yesSECURITY AND PRIVACY, Volume 9, Issue 6, November/December 2026.
ABSTRACT A retrieval‐based deep hybrid model couples a learned encoder with a non‐parametric k‐nearest‐neighbors module that, at inference time, retrieves training records and conditions its predictions on the local neighborhood. Despite strong results on tabular benchmarks, such hybrids and several recent deep tabular architectures have not been ...
Bimal Parakkal   +2 more
wiley   +1 more source

Myelination and Remyelination in Peripheral Nerve Injury: Mechanisms, Regulation, and Therapeutic Perspectives

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Peripheral nerve injury triggers axonal degeneration, myelin breakdown, and Schwann cell reprogramming. Remyelination requires reactivation of the SOX10–OCT6–KROX20/EGR2 transcriptional hierarchy, axonal NRG1–ErbB2/3 signaling, metabolic support, and coordinated immune regulation.
Li‐Xin Huang   +13 more
wiley   +1 more source

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