Results 21 to 30 of about 13,909 (173)

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

open access: yesJournal of Translational Medicine, 2008
Background Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis ...
Contaldo Franco   +9 more
doaj   +1 more source

Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia
Objective: To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis. Methods: A prospective design was performed including 49 patients submitted to hysterectomy.
Andreia Jacobo   +4 more
doaj   +1 more source

Transforming growth factor-β1 and TGF-β2 act synergistically in the fibrotic pathway in oral submucous fibrosis: An immunohistochemical observation

open access: yesIndian Journal of Medical and Paediatric Oncology, 2015
Background and objectives: Oral Submucous Fibrosis (OSF) is a potentially malignant oral disorder which leads to fibrosis of the oral mucosa and has a high rate of malignant transformation.
Venkatesh Viswanath Kamath   +3 more
doaj   +1 more source

Differences in Hypertrophic Scar Fibroblasts according to Scar Severity: Expression of Transforming Growth Factor beta1 at the mRNA and Protein Levels [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2015
Background Hypertrophic scars result from excessive collagen deposition and increased transforming growth factor beta-1 (TGF-beta1) levels. We hypothesized that the expression of TGF-beta1 mRNA and protein would increase with the clinical severity of ...
Se Young Kim   +3 more
doaj   +1 more source

Association between Genetic Variants of Transforming Growth Factor-β1 and Susceptibility of Pneumoconiosis: A Meta-analysis

open access: yesChinese Medical Journal, 2017
Background: Transforming growth factor-beta 1 (TGF-β1) and gene variants have been extensively studied in various human diseases. For example, TGF-β1 polymorphisms were associated with fibrosis and pneumoconiosis, but the data remained controversial. The
Chang-Wen Deng   +5 more
doaj   +1 more source

Smad4 and ERK2 stimulated by transforming growth factor beta1 in rhabdomyosarcoma

open access: yesChinese Medical Journal, 2007
Transforming growth factor beta (TGF-beta) plays an essential role in the regulation of normal physiologic processes of cells. TGF-beta has been shown to regulate several mitogen-activated protein kinases (MAPK) pathways in several epithelial cells. However, the effects of TGF-beta on soft tissue sarcoma are seldom reported.
Hua, Guo   +5 more
openaire   +2 more sources

Arrest of endotoxin-induced hypotension by transforming growth factor beta1. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1996
Septic shock is a cytokine-mediated process typically caused by a severe underlying infection. Toxins generated by the infecting organism trigger a cascade of events leading to hypotension, to multiple organ system failure, and frequently to death. Beyond supportive care, no effective therapy is available for the treatment of septic shock. Nitric oxide
M A, Perrella   +10 more
openaire   +2 more sources

Shen-Kang protects against tacrolimus-induced renal injury [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a rat model of chronic tacrolimus ...
Long Ye Zhang   +9 more
doaj   +1 more source

Effect of EDTA on TGF-β1 released from the dentin matrix and its influence on dental pulp stem cell migration

open access: yesBrazilian Oral Research
: Bioactive molecules stored in dentin, such as transforming growth factor beta1 (TGF-b1), may be involved in the signaling events related to dental tissue repair.
Lidiany Freitas GONÇALVES   +7 more
doaj   +1 more source

Low-dose interleukin-2 reverses chronic migraine-related sensitizations through peripheral interleukin-10 and transforming growth factor beta-1 signaling

open access: yesNeurobiology of Pain, 2022
Low-dose interleukin-2 (LD-IL-2) treatment has been shown to effectively reverse chronic migraine-related behaviors and the sensitization of trigeminal ganglion (TG) neurons through expansion and activation of peripheral regulatory T cells (Tregs) in ...
Zhaohua Guo   +5 more
doaj   +1 more source

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