Results 101 to 110 of about 1,084,742 (347)
Содержание факторов роста в пульпе постоянных зубов при хроническом пульпите
Эндодонтия Today, 2020 In the present work the maintenance of a major fibroblast growth factor-β, insulin growth factor-1, transforming growth factor -1β in gomogenates pulps of a constant teeth in norm has been studied and at an chronic inflammation.
doaj
Deferoxamine synergizes with transforming growth factor-β signaling in chondrogenesis
Genetics and Molecular Biology, 2017 Osteoarthritis, also known as degenerative arthritis or degenerative joint disease, is an epidemic disease that affects millions of people worldwide. Despite extensive recent work on the cellular biology of osteoarthritis, the precise mechanisms involved
Zheng Huang, Guangxu He, Yanke Huang
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Epithelial-Mesenchymal Transition and Metastasis under the Control of Transforming Growth Factor β
International Journal of Molecular Sciences, 2018 Metastasis of tumor cells from primary sites of malignancy to neighboring stromal tissue or distant localities entails in several instances, but not in every case, the epithelial-mesenchymal transition (EMT).
Yutaro Tsubakihara, A. Moustakas
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Endogenous transforming growth factor β1 suppresses inflammation and promotes survival in adult CNS [PDF]
, 2007 Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system.
Bauer, K +12 more
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The roles of transforming growth factor-β, Wnt, Notch and hypoxia on liver progenitor cells in primary liver tumours [PDF]
, 2014 Primary liver tumours have a high incidence and mortality. The most important forms are hepatocellular carcinoma and intrahepatic cholangiocarcinoma, both can occur together in the mixed phenotype hepatocellular-cholangiocarcinoma. Liver progenitor cells
Bogaerts, Eliene +4 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
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Quantitative analysis of transient and sustained transforming growth factor‐β signaling dynamics
Molecular Systems Biology, 2011 Mammalian cells can decode the concentration of extracellular transforming growth factor‐β (TGF‐β) and transduce this cue into appropriate cell fate decisions.
Zhike Zi +7 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Frontiers in Immunology, 2018 Inhibitory cytokines, such as transforming growth factor-β (TGF-β) and interleukin-10 (IL-10), are humoral factors involved in the suppressive function of regulatory T cells and play critical roles in maintaining immune homeostasis. However, TGF-β and IL-
T. Komai +8 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source