Results 91 to 100 of about 1,084,742 (347)

THE ROLE OF CYTOKINES AND AGMATINE IN THE DEVELOPING PLACENTA WITH PHYSIOLOGICAL AND PREGNANCY COMPLICATED

Медицинский вестник Юга России, 2013
Purpose: To study the content of cytokines and agmatine in the development of the placenta in physiological and complicated gestation.Materials and Methods: 57 women, of which 34 women with physiological pregnancy and 23 women with placental ...
A. S. Degtyareva, I. I. Krukier, E. V. Narezhnaya, V. V. Avrutskaya, M. A. Levkovich, A. A. Nikashina   +5 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

TG-interacting factor is required for the differentiation of preadipocytes

Journal of Lipid Research, 2008
The accumulation of visceral adipose tissue is closely associated with insulin resistance and metabolic syndrome. Therefore, it is important to identify genes that are required for adipocyte differentiation.
Takahiro Horie, Koh Ono, Minako Kinoshita, Hitoo Nishi, Kazuya Nagao, Teruhisa Kawamura, Yukiko Abe, Hiromichi Wada, Akira Shimatsu, Toru Kita, Koji Hasegawa   +10 more
doaj   +1 more source

Infeksi Cacing Tidak Berpengaruh terhadap Kadar Transforming Growth Factor (TGF)-β dan Kejadian Dermatitis Atopik pada Anak

Jurnal Kedokteran Brawijaya, 2015
Infeksi cacing melalui kemampuannya memacu proliferasi sel T regulator dilaporkan dapat mempengaruhi manifestasi klinik dari alergi. Selain Interleukin (IL)-10, Transforming Growth Factor (TGF)-β merupakan sitokin yang di lepaskan oleh sel T regulator.
Nadiah Soleman Mukhasin, Sitti Wahyuni, Faridha S Ilyas, Safruddin Amin, R Satriono, Farida Tabri   +5 more
openaire   +2 more sources

Transforming growth factor-β in stem cells and tissue homeostasis

Bone Research, 2018
TGF-β 1–3 are unique multi-functional growth factors that are only expressed in mammals, and mainly secreted and stored as a latent complex in the extracellular matrix (ECM).
Xin Xu, Liwei Zheng, Q. Yuan, G. Zhen, Janet L. Crane, Xuedong Zhou, Xu Cao   +6 more
semanticscholar   +1 more source

MicroRNA-483 amelioration of experimental pulmonary hypertension. [PDF]

, 2020
Endothelial dysfunction is critically involved in the pathogenesis of pulmonary arterial hypertension (PAH) and that exogenously administered microRNA may be of therapeutic benefit.
Bai, Liang, Chen, Shanshan, Chou, Chih-Hung, Cui, Xiaopei, Fan, Fenling, Gongol, Brendan, Gu, Mingxia, He, Ming, He, Yangyang, Huang, Hsien-Da, Jing, Zhi-Cheng, Lei, Yuyang, Li, Zhao, Malhotra, Atul, Miao, Yifei, Rabinovitch, Marlene, Shen, Yuan, Shyy, John Y-J, Wang, Xiaojian, Yan, Xiaosong, Zhang, Jiao, Zhang, Jin, Zhang, Yixin   +22 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Repair of the airway epithelium: Potential opportunities for therapeutic intervention in airway disease

Allergology International, 1998
The epithelium of the airway has considerable capacity to undergo repair. These repair processes are responsible for maintaining and restoring function after injury of the airways, which likely occurs often as a result of infectious, toxic or other ...
Stephen I. Rennard
doaj   +1 more source

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR, Huynh H, Munetoshi Kanayama, Ohtsuki T, Ohtsuki T, Pierro E, Sakae Takeuchi, Shiraga M, Sumio Takahashi, Takaoka M, Tetsuya Maekawa   +10 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source