Results 61 to 70 of about 1,084,742 (347)

Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough

Respiratory Research, 2009
In patients with chronic idiopathic cough, there is a chronic inflammatory response together with evidence of airway wall remodelling and an increase in airway epithelial nerves expressing TRPV-1.
Lee Kang-Yun, Nassenstein Christina, Hew Mark, Macedo Patricia, Xie Shaoping, Chung Kian   +5 more
doaj   +1 more source

Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems [PDF]

, 2007
The expansion of chondrocytes in automated bioreactors for clinical use requires that a relevant number of cells be generated, starting from variable initial seeding densities in one passage and using autologous serum.
Andrea Barbero, Cherubino P., Christian Candrian, Christina-Priska Sie, Eloit M, Gobbi A., Ivan Martin, Michael Heberer, Roberto Tommasini, Rupert Hagg, Silvia-Elena Francioli, Watt F.M, Wessman S.J.   +12 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Effects of the administration of pentoxifylline and prednisolone on the evolution of portal fibrogenesis secondary to biliary obstruction in growing animals: immunohistochemical analysis of the expression of TGF-β and VEGF

Clinics, 2012
OBJECTIVE: During the neonatal and infancy periods, some chronic liver diseases may lead to progressive hepatic fibrosis, which is a condition that can ultimately result in the loss of organ function and severe portal hypertension necessitating hepatic ...
Wagner de Castro Andrade, Luiz Fernando Ferraz da Silva, Maria Cecilia de Mendonça Coelho, Ana Cristina Aoun Tannuri, Venancio Avancini Ferreira Alves, Uenis Tannuri   +5 more
doaj   +1 more source

The Role of <i>L. plantarum</i> as an Immunomodulator Secretion of <i>Transforming Growth Factor</i>-β1, <i>Transforming Growth Factor</i>-β3, and <i>Interferon</i>-α Macrophages and Dermal Fibroblasts

Asian Journal of Applied Sciences, 2017
This research aims to see the effect of L.plantarum in modulating the secretion of Transforming Growth Factor-TGFβ1, TGFβ3 macrophages and fibroblasts, Interferon-IFNα macrophages, and to analyze the possibility of L.plantarum potency in supporting the process of scarless wound healing.
Rita Shintawati, Sunarjati Sudigdoadi, Tita Husnitawati Madjid, Endang Sutedja   +3 more
openaire   +2 more sources

Integrin control of the transforming growth factor-β pathway in glioblastoma [PDF]

, 2017
Transforming growth factor-β is a central mediator of the malignant phenotype of glioblastoma, the most common and malignant form of intrinsic brain tumours.
Goodman, Simon L., Hasenbach, Kathy, Maurer, Gabriele, Moch, Holger, Roth, Patrick, Schraml, Peter, Silginer, Manuela, Tabatabai, Ghazaleh, Thies, Svenja, Tritschler, Isabel, Weller, Michael   +10 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Korelasi Antara Transforming Growth Factor -Î’1 Monosit dengan Kebocoran Vaskuler pada Demam Berdarah Dengue

Jurnal Kedokteran Brawijaya, 2013
ABSTRAKSel monosit merupakan target utama infeksi virus Demam Berdarah Dengue (DBD) yang dapat memproduksi faktor vasoaktif yang mempengaruhi fungsi sel endotel dan berperan dalam kebocoran vaskuler. Transforming growth factor beta 1 (TGF-1) merupakan salah satu sitokin yang mempunyai banyak peran dalam patogenesis DBD.
Mohamad Supriatna, Haryson Tondy, Tatty Ermin, Yusrina Istanti, Kisdjamiatun RMD   +4 more
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transforming growth factor-β: Biology and application to cancer therapy [PDF]

Archive of Oncology, 2009
Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis.
Ivanović Vesna
doaj   +1 more source