Results 101 to 110 of about 9,216,194 (230)

Transforming growth factor-beta 1 responsiveness of human articular chondrocytes in vitro: normal versus osteoarthritis

, 1997
The transforming growth factor-β1 was known as having the most important influence on chondrocytes among various growth factors, being abundant in articular chondrocytes and osteocytes.
이진우, 김성재
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Association between Transforming Growth Factor β1 Gene Polymorphism and Chronic Spontaneous Urticaria [PDF]

Zagazig University Medical Journal
Background: Chronic spontaneous urticaria (CSU) is a prevalent skin disease with an unclear pathogenesis. Transforming growth factor beta 1 (TGF-β1) is an immunoregulatory cytokine potentially incorporated in autoimmune as well as inflammatory diseases ...
Amal Atta, Esraa Ahmed, Manal Fawzy, Eman Elgharabawy   +3 more
doaj   +1 more source

Transforming growth factor-β1 regulates the fate of cultured spinal cord-derived neural progenitor cells

, 2008
Objectives: We have evaluated the physiological roles of transforming growth factor-β1 (TGF-β1) on differentiation, migration, proliferation and anti-apoptosis characteristics of cultured spinal cord-derived neural progenitor cells. Methods: We have used
Jung, J. S, Kang, Kyung-Sun, Jang, M. S., Park, S. M, Kang, K. S, Kang, S. K, Kang, S. K., Jung, J. S., Park, S. M., Jang, M. S   +9 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Crosstalk between nuclear factor I-C and transforming growth factor-β1 signaling regulates odontoblast differentiation and homeostasis. [PDF]

, 2011
Transforming growth factor-β1 (TGF-β1) signaling plays a key role in vertebrate development, homeostasis, and disease. Nuclear factor I-C (NFI-C) has been implicated in TGF-β1 signaling, extracellular matrix gene transcription, and tooth root development.
Yoon Won-Joon, Won-Joon Yoon, Lee Dong-Seol, Cho Moon-Il, 박주철, Moon-Il Cho, Park, Joo-Cheol, Lee, Dong-Seol, Richard M. Gronostajski, Dong-Seol Lee, Kim, Heung-Joong, Richard M Gronostajski, Eui Sic Cho, Cho, Moon-Il, Kim Heung-Joong, Yoon, Won-Joon, Joo-Cheol Park, Gronostajski Richard M., Park Joo-Cheol, Cho, Eui Sic, Gronostajski, Richard M., Heung-Joong Kim, Cho Eui Sic   +22 more
core   +2 more sources

High‐Throughput Data Generation and Transfer Learning Enabled Microstructure‐Property Integrated Design of Nickel‐Based Powder Metallurgy Superalloy

Advanced Science, EarlyView.
An integrated transfer learning framework integrates CALPHAD simulations, diffusion‐multiple experiments, and literature data to predict long‐term microstructural stability and short‐term mechanical properties of Ni‐based powder metallurgy superalloys. Based on these model predictions, a high‐performance, low‐density alloy, USTB‐PM750, is designed from
Zixin Li, Hongtao Zhang, Zichao Peng, Yuheng Zhang, Qian Lv, Yihuan Cao, Xuqing Wang, Huadong Fu, Jianxin Xie   +8 more
wiley   +1 more source

Nerve growth factor regulates transforming growth factor-β1 gene expression by both transcriptional and posttranscriptional mechanisms in PC12 cells

, 2002
PC12 cells express two transforming growth factor (TGF)-β1 transcripts, 1.7 and 2.5 kb in size. Other TGF-βs are expressed at much lower levels. Incubation with nerve growth factor (NGF) produced a time- and dose-dependent increase in content of TGF-β1 ...
Aranda, Ana, Cosgaya, José Miguel, Ana Aranda, Jose Miguel Cosgaya   +3 more
core   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source