Results 21 to 30 of about 53,894 (256)

Pre-reproductive stress in adolescent female rats alters maternal care and DNA methylation patterns across generations

open access: yesStress, 2023
Stress during development affects maternal behavior and offspring phenotypes. Stress in adolescence is particularly consequential on brain development and maturation, and is implicated in several psychiatric disorders.
Hiba Zaidan   +4 more
doaj   +1 more source

Can environmental conditions experienced in early life influence future generations? [PDF]

open access: yes, 2014
The consequences of early developmental conditions for performance in later life are now subjected to convergent interest from many different biological sub-disciplines.
Burton, Tim, Metcalfe, Neil B.
core   +1 more source

Family Genealogy’s Contributions to the Philosophical Problem of Birth

open access: yesGenealogy, 2018
The central philosophical problem of birth concerns the fact that it is an event necessary for all events. As such, it is the nihilated a priori of itself—in short, it is lost in an abyss of consciousness.
Stephen B. Hatton
doaj   +1 more source

DNA methylation and hydroxymethylation have distinct genome-wide profiles related to axonal regeneration

open access: yesEpigenetics, 2021
Alterations in environmentally sensitive epigenetic mechanisms (e.g., DNA methylation) influence axonal regeneration in the spinal cord following sharp injury.
Andy Madrid   +6 more
doaj   +1 more source

Cumulative Metabolic and Epigenetic Effects of Paternal and/or Maternal Supplementation with Arachidonic Acid across Three Consecutive Generations in Mice

open access: yesCells, 2022
Apart from the known associations between arachidonic acid (AA), weight gain, and neurological and immune function, AA exposure leads to alterations in global and gene-specific DNA methylation (DNAm) and fatty acid (FA) content in human cultured cells ...
Carmen de la Rocha   +9 more
doaj   +1 more source

Is the growth of the child of a smoking mother influenced by the father's prenatal exposure to tobacco? A hypothesis generating longitudinal study [PDF]

open access: yes, 2014
OBJECTIVES: Transgenerational effects of different environmental exposures are of major interest, with rodent experiments focusing on epigenetic mechanisms. Previously, we have shown that if the study mother is a non-smoker, there is increased mean birth
Golding, Jean   +4 more
core   +2 more sources

Maternal obesity has little effect on the immediate offspring but impacts on the next generation [PDF]

open access: yes, 2013
Maternal obesity during pregnancy has been linked to an increased risk of obesity and cardiometabolic disease in the offspring, a phenomenon attributed to developmental programming. Programming effects may be transmissible across generations through both
Dakin, Rachel S.   +7 more
core   +1 more source

Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis [PDF]

open access: yes, 2018
Background. The lead (Pb) exposure crisis in Flint, Michigan has passed from well-publicized event to a footnote, while its biological and social impact will linger for lifetimes.
Bayon, Baindu L.   +3 more
core   +2 more sources

Rural alternatives for local development: An intercultural analysis (case study from northern Ecuador)

open access: yesJournal of Agriculture and Rural Development in the Tropics and Subtropics, 2022
This study takes a historical and analytical tour of the experiences, ways of life and community knowledge oriented towards the construction of alternatives to achieve development in the communities of Cotacachi and Yunguilla, Ecuador.
Anita Krainer   +2 more
doaj   +1 more source

From Linear Genes to Epigenetic Inheritance of Three-dimensional Epigenomes [PDF]

open access: yes, 2011
Fifty years ago Jacob and Monod reported their findings on the regulation of gene activity. Working on lambda bacteriophage lysogeny and the regulation of the production of an enzyme that cleaves lactose, they observed that its production was induced by ...
Cavalli, Giacomo
core   +3 more sources

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