Germline transgenesis and insertional mutagenesis in Schistosoma mansoni mediated by murine leukemia virus. [PDF]
PLoS Pathogens, 2012 Functional studies will facilitate characterization of role and essentiality of newly available genome sequences of the human schistosomes, Schistosoma mansoni, S. japonicum and S. haematobium.
Gabriel Rinaldi +9 more
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Agrobacterial rol genes modify thermodynamic and structural properties of starch in microtubers of transgenic potato [PDF]
, 2010 Wild-type (WT) plants of potato (Solanum tuberosum L.) and their transgenic forms carrying agrobacterial genes rolB or rolC under the control of B33 class I patatin promoter were cultured in vitro on MS medium with 2% sucrose in a controlled-climate ...
Aksenova, N.P. +9 more
core +2 more sources
Expression of RNA-interference/antisense transgenes by the cognate promoters of target genes is a better gene-silencing strategy to study gene functions in rice. [PDF]
PLoS ONE, 2011 Antisense and RNA interference (RNAi)-mediated gene silencing systems are powerful reverse genetic methods for studying gene function. Most RNAi and antisense experiments used constitutive promoters to drive the expression of RNAi/antisense transgenes ...
Jing Li +10 more
doaj +1 more source
Fluorescent protein tagging confirms the presence of ribosomal proteins atDrosophilapolytene chromosomes [PDF]
, 2013 \ud \ud Most ribosomal proteins (RPs) are stoichiometrically incorporated into ribosomal subunits and play essential roles in ribosome biogenesis and function.
Bischof +27 more
core +3 more sources
Cisgenesis, a new tool for traditional plant breeding, should be exempted from the regulation on genetically modified organisms in a step by step approach [PDF]
, 2008 Modern potato breeding requires over 100,000 seedlings per new variety. Main reasons are (1) the increasing number of traits that have to be combined in this tetraploid vegetatively propagated crop, and (2) an increasing number of traits (e.g ...
Jacobsen, E., Schouten, H.J.
core +2 more sources
Drosophila heat shock response requires the jnk pathway and phosphorylation of mixed lineage kinase at a conserved serine-proline motif [PDF]
, 2012 Defining context specific requirements for proteins and pathways is a major challenge in the study of signal transduction. For example, the stress-activated protein kinase (SAPK) pathways are comprised of families of closely related transducers that are ...
Garlena, RA, Gonda, RL, Stronach, B
core +5 more sources
Nature Communications, 2022 Long hairpin RNA (hpRNA) transgenes are the most widely used RNAi technology in plants, but are potentially subject to self-induced transcriptional silencing.
Daai Zhang +7 more
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Complex interactions between cis-regulatory modules in native conformation are critical for Drosophila snail expression [PDF]
, 2011 It has been shown in several organisms that multiple cis-regulatory modules (CRMs) of a gene locus can be active concurrently to support similar spatiotemporal expression.
Dunipace, Leslie +2 more
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Synthetic mammalian transgene negative autoregulation
Molecular Systems Biology, 2013 Biological networks contain overrepresented small‐scale topologies, typically called motifs. A frequently appearing motif is the transcriptional negative‐feedback loop, where a gene product represses its own transcription.
Vinay Shimoga +4 more
doaj +1 more source
Multi-locus assortment (MLA) for transgene dispersal and elimination in mosquito populations. [PDF]
PLoS ONE, 2009 BACKGROUND:Replacement of wild-type mosquito populations with genetically modified versions is being explored as a potential strategy to control vector-borne diseases.
Jason L Rasgon
doaj +1 more source