Results 21 to 30 of about 84,438 (207)

A Fruitful Decade Using Synthetic Promoters in the Improvement of Transgenic Plants

open access: yesFrontiers in Plant Science, 2019
Advances in plant biotechnology provide various means to improve crop productivity and greatly contributing to sustainable agriculture. A significant advance in plant biotechnology has been the availability of novel synthetic promoters for precise ...
Sajid Ali, Won-Chan Kim
doaj   +1 more source

Germline transgenesis and insertional mutagenesis in Schistosoma mansoni mediated by murine leukemia virus. [PDF]

open access: yesPLoS Pathogens, 2012
Functional studies will facilitate characterization of role and essentiality of newly available genome sequences of the human schistosomes, Schistosoma mansoni, S. japonicum and S. haematobium.
Gabriel Rinaldi   +9 more
doaj   +1 more source

Expression of RNA-interference/antisense transgenes by the cognate promoters of target genes is a better gene-silencing strategy to study gene functions in rice. [PDF]

open access: yesPLoS ONE, 2011
Antisense and RNA interference (RNAi)-mediated gene silencing systems are powerful reverse genetic methods for studying gene function. Most RNAi and antisense experiments used constitutive promoters to drive the expression of RNAi/antisense transgenes ...
Jing Li   +10 more
doaj   +1 more source

Rethinking the Risk Management Process for Genetically Engineered Crop Varieties in Small-scale, Traditionally Based Agriculture

open access: yesEcology and Society, 2005
Proponents of genetically engineered (GE) crops often assume that the risk management used in the industrial world is appropriate for small-scale, traditionally based agriculture in the Third World. Opponents of GE crops often assume that risk management
David A. Cleveland, Daniela Soleri
doaj   +1 more source

Multi-locus assortment (MLA) for transgene dispersal and elimination in mosquito populations. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Replacement of wild-type mosquito populations with genetically modified versions is being explored as a potential strategy to control vector-borne diseases.
Jason L Rasgon
doaj   +1 more source

Nucleotide mismatches prevent intrinsic self-silencing of hpRNA transgenes to enhance RNAi stability in plants

open access: yesNature Communications, 2022
Long hairpin RNA (hpRNA) transgenes are the most widely used RNAi technology in plants, but are potentially subject to self-induced transcriptional silencing.
Daai Zhang   +7 more
doaj   +1 more source

Measurement of Transgenes Copy Number in Wheat Plants Using Droplet Digital PCR

open access: yesBio-Protocol, 2022
Genetic transformation is a powerful method for the investigation of gene function and improvement of crop plants. The transgenes copy number in the transgenic line is involved in gene expression level and phenotypes.
Peng Liu   +4 more
doaj   +1 more source

Transgenes and their contributions to epigenetic research [PDF]

open access: yes, 2013
Shortly after gene transfer technologies had been established for different plant species, the first reports emerged about transgenes showing unexpected segregation patterns due to unstable expression.
Meyer, P
core   +1 more source

Synthetic mammalian transgene negative autoregulation

open access: yesMolecular Systems Biology, 2013
Biological networks contain overrepresented small‐scale topologies, typically called motifs. A frequently appearing motif is the transcriptional negative‐feedback loop, where a gene product represses its own transcription.
Vinay Shimoga   +4 more
doaj   +1 more source

Matrix metalloproteinase-20 over-expression is detrimental to enamel development: a Mus musculus model. [PDF]

open access: yesPLoS ONE, 2014
Matrix metalloproteinase-20 (Mmp20) ablated mice have enamel that is thin and soft with an abnormal rod pattern that abrades from the underlying dentin.
Masashi Shin   +8 more
doaj   +1 more source

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