Results 31 to 40 of about 80,448 (304)
Matrix metalloproteinase-20 over-expression is detrimental to enamel development: a Mus musculus model. [PDF]
PLoS ONE, 2014 Matrix metalloproteinase-20 (Mmp20) ablated mice have enamel that is thin and soft with an abnormal rod pattern that abrades from the underlying dentin.
Masashi Shin +8 more
doaj +1 more source
Frontiers in Genome Editing, 2023 Increased understanding of plant genetics and the development of powerful and easier-to-use gene editing tools over the past century have revolutionized humankind’s ability to deliver precise genotypes in crops.
Zuzana Kocsisova, Viktoriya Coneva
doaj +1 more source
New approaches for characterization of the genetic stability of vaccine cell lines
Human Vaccines & Immunotherapeutics, 2017 The genetic stability of cell lines is a critical analytical attribute required to demonstrate the quality of cells over time. During cell passage, mutations can arise in the genomic DNA, potentially leading to changes in the final vaccine product.
Siemon Ng, Lucy Gisonni-Lex, Ali Azizi
doaj +1 more source
Transgenes used for Double RNAi.
, 2019 Transgenes used for Double RNAi.
Kim S. McKim (243877) +2 more
core +1 more source
Frontiers in Plant ScienceIntroductionBidirectional gene flow via pollen between transgenic rice and weedy rice could occur in natural fields. Gene flow from transgenic rice to weedy rice has been confirmed in many studies, and thus results showed that F1 hybrids could persist in
Guang-Le Xie +7 more
doaj +1 more source
eLife, 2016 Changes in chromosome number impair fitness by disrupting the balance of gene expression. Here we analyze mechanisms to compensate for changes in gene dose that accompanied the evolution of sex chromosomes from autosomes.
Bayly S Wheeler +5 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2022 Human primary cells, including urine-derived cells (UCs), are an excellent source for generation of pluripotent stem cells (iPSCs) to model disease. However, replicative senescence starts early and shortens the time window for generation of iPSCs.
Matthias Weiand +4 more
doaj +1 more source
Inheritance of GFP-Bt transgenes from
, 2004 Transgenes from transgenic oilseed rape, Brassica napus (AACC genome), can introgress into populations of wild B. rapa (AA genome), but little is known about the long-term persistence of transgenes from different transformation events.
Matthew D. Halfhill +6 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A built-in mechanism to mitigate the spread of insect-resistance and herbicide-tolerance transgenes into weedy rice populations. [PDF]
PLoS ONE, 2012 BACKGROUND: The major challenge of cultivating genetically modified (GM) rice (Oryza sativa) at the commercial scale is to prevent the spread of transgenes from GM cultivated rice to its coexisting weedy rice (O. sativa f. spontanea).
Chengyi Liu +5 more
doaj +1 more source