Results 121 to 130 of about 4,740,665 (262)

Systematic Evaluation of Mesophyll Protoplast Isolation and PEG-Mediated Transient Expression in <i>Rosa chinensis</i> 'Old Blush'. [PDF]

Plants (Basel)
Zhao Y, Zhong Y, Hou F, El-Kassaby YA, Zhang D.   +4 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The crucible, 1934-12

, 2020
Gary Transient Shelter
core  

Co-Transfected Plasmids Enhance Transient Expression of Reporter Genes. [PDF]

BioTech (Basel)
Lo SY, Yang CH, Chan YR, Chao YT, Lai MJ, Li HC.   +5 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A Fluorescence-Based Transient Expression Assay for the Analysis of Upstream Open Reading Frames in Plants. [PDF]

Plant Direct
Haas BE, Saif F, Bolger E, Doran L, Rosales E, Kim A, Burgess SJ, Long SP.   +7 more
europepmc   +1 more source

Protoplast transient expression-based RNA-sequencing: A simple method to screen transcriptional regulation in plants. [PDF]

Plant Physiol, 2023
Zhu J, Li S, Jiang H, Lv D, Ma S, Wang B, Lu X, Yang W, Chen R, Zhou X.   +9 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

The crucible, 1934-10

, 2020
Gary Transient Shelter
core  

Causes and consequences of experimental variation in Nicotiana benthamiana transient expression. [PDF]

Nat Commun
Tang SN, Szarzanowicz MJ, Lanctot A, Sirirungruang S, Kirkpatrick LD, Drako K, Alamos S, Cheng L, Waldburger LM, Liu S, Huang L, Kazaz S, Akyuz Turumtay E, Baidoo E, Eudes A, Thompson MG, Shih PM.   +16 more
europepmc   +1 more source