Results 41 to 50 of about 11,438 (267)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Modeling and Simulation of High Voltage Power Lines under Transient and Persistent Faults

Mathematics, 2022
The work proposes an original method for modeling and simulating the triggering of 110 kV interconnection power lines in case of common faults, such as transient or persistent faults.
Marius Fișcă, Mihail Abrudean, Vlad Mureșan, Iulia Clitan, Mihaela-Ligia Ungureșan, Roxana Motorga, Emilian Ceuca   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Transient Fault Detection in Networked Control Systems [PDF]

International Journal of Distributed Sensor Networks, 2014
Transient faults appear unpredictablly and frequently in networked control systems (NCSs), which directly affect the safety of system. However, they can not be accurately identified due to various kinds of causes, so the detection of them needs more systematic and comprehensive system knowledge.
Xiong-Feng Huang, Chunjie Zhou, Shuang Huang, Kai-Xing Huang, Xuan Li   +4 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Rolling Bearing Fault Feature Extraction Based on Adaptive Tunable Q-Factor Wavelet Transform and Spectral Kurtosis

Shock and Vibration, 2020
The fault feature of the rolling bearing is difficult to extract when weak fault occurs and interference exists. The tunable Q-factor wavelet transform (TQWT) can effectively extract the weak fault characteristic of the rolling bearing, but the manual ...
Jianlong Zhao, Yongchao Zhang, Qingguang Chen   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Field experiment using transient energy method to locate a single-phase to ground fault

Global Energy Interconnection, 2020
Distribution networks in China and several other countries are predominantly neutral inefficiently grounding systems (NIGSs), and more than 80% of the faults in distribution networks are single-phase-to-ground (SPG) faults.
Wei Xie, Xuewen Wang, Chen Fang, Hengxu Zhang, Fang Shi, Xiaodong Xing, Baicong Sun   +6 more
doaj   +1 more source

A low-cost testing for transient faults

Ubiquity, 2006
Unconventional and low - cost software implemented testing technique for processor transient faults are briefly discussed here. On-line signatures of the Processor Status Register have been used here for detecting transient faults.
openaire   +1 more source