Results 61 to 70 of about 11,438 (267)

A Fault Detection Method for Multiterminal Flexible DC Grids Based on Current Transient Energy Rate Ratio

International Transactions on Electrical Energy Systems
To address the challenge of weak fault transient characteristics in multiterminal flexible DC grids caused by transition resistance, DC reactors, and noise interference, which render traditional single-electrical-quantity detection methods ineffective ...
Renwu Yan, Zhonghong Liu, Luebin Fang, Ning Yu, Zibin Su   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Enhancing Transient Stability of DFIG-Based Wind Turbine Systems Using Deep Learning-Controlled Resistance-Based Fault Current Limiters [PDF]

Advances in Engineering and Intelligence Systems
This research addresses the challenge of grid stability when integrating renewable energy, especially wind power. It focuses on enhancing transient stability in doubly fed induction generator (DFIG) wind energy systems using advanced strategies like ...
Yaoying Wang
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Transient Modeling and Analysis of Short-Circuit Faults in the DC Power System for Hybrid Electric Aircraft

Aerospace
Transient modeling of short-circuit faults in the DC power system of hybrid electric aircraft (HEA) serves as a fundamental basis for effective fault identification, localization, and isolation.
Bin Liu, Shuguang Wei, Jiaqi Li, Kewei Chen, Feifan Xu, Hengliang Zhang   +5 more
doaj   +1 more source

Efficient fault tolerance: an approach to deal with transient faults in multiprocessor architectures

Proceedings of 1994 International Conference on Parallel and Distributed Systems, 2002
Dynamic error processing approaches are an important mechanism to increase the reliability in a multiprocessor system, while making efficient use of the available resources. To this end, dynamic error processing must be integrated with a fault treatment approach aiming at optimising resource utilisation.
Bondavalli A, Chiaradonna S, Di Giandomenico F   +2 more
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

An Analytical Short-Circuit Current Calculation Method for Full-Power Wind Turbines under Complete Fault Ride-Through Processes [PDF]

Dianli jianshe
Accurate calculation of short-circuit current throughout the fault ride-through process of wind turbines is a critical prerequisite for the analysis and control of modern power systems.
YUAN Shuai, XIAO Jiaan, TAO Jun, CUI Haohan, CHAO Pupu, LI Weixing, A Minfu, WANG Liqiang, ZHONG Ming
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source