Results 71 to 80 of about 11,438 (267)
Effective numerical simulation of fault transient system
International Journal of Modeling, Simulation, and Scientific ComputingPower systems, including synchronous generator systems, are typical systems that strive for stable operation. In this paper, we numerically study the fault transient process of a synchronous generator system based on the first benchmark model. That is, we make it clear whether an originally stable generator system can restore its stability after a ...
Sixu Wu +5 more
openaire +4 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
EnergiesWind turbines are vulnerable to negative sequence current injection, the conventional automatic reclosing scheme for wind power outgoing lines, since we may inject negative sequence components into the system and reclose it without distinguishing the ...
Sen Hu, Chao Xie, Chunya Yin
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Gong-kuang zidonghua, 2012 For the deficiency of single line selection principle, the paper proposed integrative line selection strategy, namely zero sequence admittance method, zero sequence susceptance increment method and zero sequence conductance method based on steady-state ...
LI Hui, TANG Yi, SUN Chang-qing
doaj
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
International Journal of Electrical Power & Energy SystemsAfter the single-phase high impedance fault (HIF) occurs in distribution networks, it is difficult to select the faulted feeder and locate the fault section due to the weak fault current and susceptibility to noise interference.
Ao Li +4 more
doaj +1 more source
A Reliability Scheduling Algorithm for the Static Segment of FlexRay on Vehicle Networks
Sensors, 2018 FlexRay is a next-generation in-vehicle communication protocol which works in real time with flexibility. The most common applications in FlexRay are high bandwidth. X-by-wire applications, such as brake by wire and throttle by wire. However, there is no
Trong-Yen Lee +3 more
doaj +1 more source