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Transient Receptor Potential (TRP) Cation Channels in Diabetes
Current Topics in Medicinal Chemistry, 2013Transient Receptor Potential (TRP) proteins constitute a family of cation channels with very diverse permeation and gating properties. Likewise they have a very diverse role in mammalian physiology ranging from sensory nerve endings, the cardiac muscle to immune cells.
Barbara, Colsoul +2 more
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Transient Receptor Potential (TRP) Channels☆
2015A. Riccio, J.F. Doerner, D.E. Clapham
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Transient receptor potential (TRP) channel function in the reproductive axis
Cell Calcium, 2017Transient receptor potential (TRP) channels play important functional roles in the signal transduction machinery of hormone-secreting cells and have recently been implicated in reproductive physiology. While expression studies have demonstrated TRP channel expression at all levels of the hypothalamic-pituitary-gonadal (hpg) axis, functional details ...
Viktoria, Götz +3 more
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Transient receptor potential (TRP) channels as potential drug targets in respiratory disease
Cell Calcium, 2003Calcium-permeable channels have traditionally been thought of as therapeutic targets in excitable cells. For instance, voltage-operated Ca2+ channels in neurones and smooth muscle cells for neurological and cardiovascular diseases although calcium-permeable channels are also functionally important in electrically non-excitable cells.
Su, Li, John, Westwick, Chris, Poll
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Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Journal of Neural TransmissionPsychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyperactivity disorder, as well as neurological disorders such as Migraine, are linked by the evidence of altered calcium homeostasis. The disturbance of intra-cellular calcium homeostasis disrupts the activity of numerous ion channels ...
Veerta Sharma +2 more
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Modulation of Transient Receptor Potential (TRP) Channels by Chinese Herbal Extracts
Phytotherapy Research, 2011Many transient receptor potential (TRP) channels are activated or blocked by various compounds found in plants. TRPV1 (transient receptor potential vanilloid 1) and transient receptor potential ankyrin 1 (TRPA1) are members of the TRP ion channel family which are implicated as cough receptors.
Yansong, Zhang +6 more
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High-throughput screening of transient receptor potential (TRP) channels in pterygium
International OphthalmologyPterygium is a hyaline degenerative disease of the conjunctiva characterized by the progression of fibrovascular connective tissue from the bulbar conjunctiva to the cornea. The mechanism of pterygium formation is still not fully understood. Transient receptor potential (TRP) channels are a group of ion channels with distinct characteristics.
Ibrahim Erbağcı, Seydi Okumus
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The role of transient receptor potential (TRP) channels in phagocytosis: A comprehensive review
European Journal of PharmacologyWhen host cells are exposed to foreign particles, dead cells, or cell hazards, a sophisticated process called phagocytosis begins. During this process, macrophages, dendritic cells, and neutrophils engulf the target by expanding their membranes. Phagocytosis of apoptotic cells is called efferocytosis.
Mohaddeseh Sadat Alavi +2 more
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