Results 81 to 90 of about 5,388,665 (365)

Current landscape of mRNA technologies and delivery systems for new modality therapeutics

Journal of Biomedical Science
Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects.
Ruei-Min Lu, Hsiang-En Hsu, Ser John Lynon P. Perez, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Yin-Shiou Lin, Ching-Hang Liu, Shih-Han Ko, Christian Angelo P. Concio, Yi-Jen Su, Yi-Han Chang, Wen-Shan Li, Han-Chung Wu   +13 more
doaj   +1 more source

Frailty, delirium and hospital mortality of older adults admitted to intensive care: the Delirium (Deli) in ICU study

Critical Care, 2020
Background Clinical frailty among older adults admitted to intensive care has been proposed as an important determinant of patient outcomes. Among this group of patients, an acute episode of delirium is also common, but its relationship to frailty and ...
David Sanchez, Kathleen Brennan, Masar Al Sayfe, Sharon-Ann Shunker, Tony Bogdanoski, Sonja Hedges, Yu Chin Hou, Joan Lynch, Leanne Hunt, Evan Alexandrou, Manoj Saxena, Simon Abel, Ramanathan Lakshmanan, Deepak Bhonagiri, Michael J. Parr, Anders Aneman, Danielle Ni Chroinin, Kenneth M. Hillman, Steven A. Frost   +18 more
doaj   +1 more source

Addressing the quality of paediatric primary care: health worker and caregiver perspectives from a process evaluation of PACK child, a health systems intervention in South Africa

BMC Pediatrics, 2021
Background The WHO’s Integrated Management of Childhood Illness (IMCI) has resulted in progress in addressing infant and child mortality. However, unmet needs of children continue to present a burden upon primary healthcare services.
Robyn Curran, Jamie Murdoch, Max Bachmann, Eric Bateman, Ruth Cornick, Sandra Picken, Makhosazana Lungile Simelane, Lara Fairall   +7 more
doaj   +1 more source

Technical Infrastructures of Historical Translation Knowledge: A Call for the use of the Digital Library and Bibliography of Literature in Translation

Chronotopos, 2022
Editorial in English and German on the technical infrastructures relevant for translation history. The editors share an invitation to make use of the Digital Library and Bibliography of Literature in Translation (DLBT) and discuss the needs of ...
Larisa Schippel, Julia Richter, Tomasz Rozmyslowicz , Stefanie Kremmel   +3 more
doaj   +1 more source

Findings of the WMT24 General Machine Translation Shared Task: The LLM Era Is Here but MT Is Not Solved Yet

Conference on Machine Translation
This overview paper presents the results of the General Machine Translation Task organised as part of the 2024 Conference on Machine Translation (WMT).
Tom Kocmi, Eleftherios Avramidis, Rachel Bawden, Ondrej Bojar, Anton Dvorkovich, C. Federmann, Mark Fishel, Markus Freitag, Thamme Gowda, Roman Grundkiewicz, B. Haddow, Marzena Karpinska, Philipp Koehn, Benjamin Marie, C. Monz, Kenton Murray, Masaaki Nagata, M. Popel, Maja Popovic, Mariya Shmatova, Steinþór Steingrímsson, Vilém Zouhar   +21 more
semanticscholar   +1 more source

Minimum Error Rate Training in Statistical Machine Translation

Annual Meeting of the Association for Computational Linguistics, 2003
Often, the training procedure for statistical machine translation models is based on maximum likelihood or related criteria. A general problem of this approach is that there is only a loose relation to the final translation quality on unseen text.
F. Och
semanticscholar   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

To Translate or not to Translate? [PDF]

Meta: Journal des traducteurs, 1985
A partir d'exemples sur les difficultes de la traduction tirees de la litterature et en particulier de la poesie («les correspondances» de Baudelaire), est recense l'ensemble des problemes, souvent incontournables que pose la langue a un traducteur charge de trouver d'une langue a une autre un concept ...
openaire   +2 more sources

Recognition of RNA N6-methyladenosine by IGF2BP Proteins Enhances mRNA Stability and Translation

Nature Cell Biology, 2018
N6-methyladenosine (m6A) is the most prevalent modification in eukaryotic messenger RNAs (mRNAs) and is interpreted by its readers, such as YTH domain-containing proteins, to regulate mRNA fate.
Huilin Huang, Hengyou Weng, Wen-Ju Sun, Xi Qin, Hailing Shi, Huizhe Wu, B. Zhao, Ana Mesquita, Chang Liu, Celvie L. Yuan, Yueh-Chiang Hu, S. Hüttelmaier, Jennifer Skibbe, R. Su, Xiaolan Deng, Lei Dong, Miao Sun, Chenying Li, S. Nachtergaele, Yungui Wang, Chao Hu, Kyle Ferchen, K. Greis, Xi Jiang, M. Wei, Lianghu Qu, J. Guan, Chuan He, Jianhua Yang, Jianjun Chen   +29 more
semanticscholar   +1 more source

On the coexistence and complementarity of Chinese translation methods of English metrical poetry [PDF]

, 2010
The Chinese translation of English metrical poetry has a history of more than one hundred years, but it is still controversial on how to translate English metrical poetry into Chinese.
Feng Ruizhen,, Gao Shaole,, Gu Sen,, Li Chongyue,   +3 more
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