AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
A Structured Computational Roadmap for Lipidomics in R: Reproducible Workflows from Raw Data to Functional Insight. [PDF]
Papatheodorou MP, Vlamos P, Krokidis MG.
europepmc +1 more source
Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo +11 more
wiley +1 more source
A transcriptomic resource for glial GABA-associated ASH neuronal aging and candidate pathways. [PDF]
Al-Sheikh U +7 more
europepmc +1 more source
DISCUSSION ISSUES OF TRANSLATION AND LOCALIZATION OF PROPER NAMES
N. I. Chepelyuk +2 more
openaire +1 more source
All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao +8 more
wiley +1 more source
Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta-Analysis. [PDF]
Juszczak GR.
europepmc +1 more source
Mixed‐Polymer Hole Transport Layers Reinforce Au‐Anode Top Emitting Perovskite Light Emitting Diodes
Au‐anode corrosion is shown to occur rapidly under voltage bias in MAPbI3 perovskite LEDs. Resulting Au+ migration quickly leads to device shorting and unstable emission during constant current driving. We demonstrate that using a simple mixed‐polymer hole transport layer containing polyTPD and PVK can reduce Au‐corrosion and stabilize LED operation ...
James C. Loy +5 more
wiley +1 more source
Overseas reception of English translations of Journey to the West: Temporal dynamics, cross-platform sentiment patterns, and topic modeling. [PDF]
Jia N, Xin J, Wang Y.
europepmc +1 more source
Light and Shadows: Insights from Large-Scale Visual Screens for Arabidopsis Leaf Morphology Mutants. [PDF]
Juan-Vicente L, Ruiz-Bayón A, Micol JL.
europepmc +1 more source

