Results 11 to 20 of about 13,603 (194)

Evolution of Transmissible Gastroenteritis Virus (TGEV): A Codon Usage Perspective. [PDF]

Int J Mol Sci, 2020
Transmissible gastroenteritis virus (TGEV) is a coronavirus associated with diarrhea and high mortality in piglets. To gain insight into the evolution and adaptation of TGEV, a comprehensive analysis of phylogeny and codon usage bias was performed. The phylogenetic analyses of maximum likelihood and Bayesian inference displayed two distinct genotypes ...
Cheng S, Wu H, Chen Z.
europepmc   +6 more sources

A new circular RNA-encoded protein BIRC6-236aa inhibits transmissible gastroenteritis virus (TGEV)-induced mitochondrial dysfunction. [PDF]

J Biol Chem, 2022
Transmissible gastroenteritis virus (TGEV), a member of the coronavirus family, is the pathogen responsible for transmissible gastroenteritis, which results in mitochondrial dysfunction in host cells. Previously, we identified 123 differentially expressed circular RNAs (cRNA)from the TGEV-infected porcine intestinal epithelial cell line jejunum 2 (IPEC-
Zhao X, Guo J, Wang X, Lin J, Liu Z, Xu C, Zhang D, Tong D.   +7 more
europepmc   +5 more sources

All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Inflammation in IPEC-J2 Cells via Suppressing the RLRs/NF‐κB Signaling Pathway

Frontiers in Immunology, 2022
Transmissible gastroenteritis virus (TGEV) infection can cause transmissible gastroenteritis (TGE), especially in suckling piglets, resulting in a significant economic loss for the global pig industry.
Junning Pu, Daiwen Chen, Gang Tian, Jun He, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Yuheng Luo, Hui Yan, Bing Yu   +11 more
doaj   +3 more sources

Transmissible Gastroenteritis Virus: An Update Review and Perspective

Viruses, 2023
Transmissible gastroenteritis virus (TGEV) is a member of the alphacoronavirus genus, which has caused huge threats and losses to pig husbandry with a 100% mortality in infected piglets.
Yiwu Chen, Yuanzhu Zhang, Xi Wang, Jian Zhou, Lerong Ma, Jianing Li, Lin Yang, Hongsheng Ouyang, Hongming Yuan, Daxin Pang   +9 more
doaj   +3 more sources

Eugenol Attenuates Transmissible Gastroenteritis Virus-Induced Oxidative Stress and Apoptosis Via ROS-NRF2-ARE Signaling

Antioxidants, 2022
Transmissible gastroenteritis virus (TGEV), a coronavirus that causes severe diarrhea due to oxidative stress in the piglet intestine, is a major cause of economic loss in the livestock industry.
Kang Wang, Yan Tang, Xiu Wu, Hongmin Liang, Daiwen Chen, Bing Yu, Jun He, Xiangbing Mao, Zhiqing Huang, Hui Yan, Aimin Wu, Yuheng Luo, Ping Zheng, Jie Yu, Huifen Wang, Junqiu Luo   +15 more
doaj   +3 more sources

Inhibition of porcine transmissible gastroenteritis virus (TGEV) replication in mini-pigs by shRNA

Virus Research, 2010
Transmissible gastroenteritis virus (TGEV) is the causative agent of porcine transmissible gastroenteritis (TGE), characterized by high mortality and severely retarded growth in piglets that dramatically affects the porcine industry. Previously, we have identified two shRNA-expressing plasmids pEGFP-U6/P1 and pEGFP-U6/P2 that target RNA-dependent RNA ...
Zhou, Junfang, Huang, Fen, Hua, Xiuguo, Cui, Li, Zhang, Wen, Shen, Yan, Yan, Yijia, Chen, Piren, Ding, Dezhong, Mou, Jing, Chen, Qi, Lan, Daoliang, Yang, Zhibiao   +12 more
openaire   +4 more sources

Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-κB activation

Virulence, 2018
Transmissible gastroenteritis virus (TGEV) infection causes acute enteritis in swine of all ages, and especially in suckling piglets. Small intestinal inflammation is considered a central event in the pathogenesis of TGEV infections, and nuclear factor ...
Li Wang, Xinyuan Qiao, Sijia Zhang, Yue Qin, Tiantian Guo, Zhenye Hao, Li Sun, Xiaona Wang, Yanan Wang, Yanping Jiang, Lijie Tang, Yigang Xu, Yijing Li   +12 more
doaj   +2 more sources

The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets

Viruses, 2019
Transmissible gastroenteritis virus (TGEV) is the etiologic agent of transmissible gastroenteritis in pigs, and the N-terminal domain of TGEV spike protein is generally recognized as both the virulence determinant and enteric tropism determinant.
Gang Wang, Rui Liang, Ziwei Liu, Zhou Shen, Jiale Shi, Yuejun Shi, Feng Deng, Shaobo Xiao, Zhen F. Fu, Guiqing Peng   +9 more
doaj   +3 more sources

Intragastric administration of attenuated Salmonella typhimurium harbouring transmissible gastroenteritis virus (TGEV) DNA vaccine induced specific antibody production

Vaccine, 2009
Attenuated Salmonella typhimurium was selected as a transgenic vehicle for the development of live mucosal vaccines against transmissible gastroenteritis virus (TGEV). A 2.2kb DNA fragment, encoding for N-terminal domain glycoprotein S of TGEV, was amplified by RT-PCR and cloned into eukaryotic expression vector pVAX1.
Yang, Heng, Cao, Sanjie, Huang, Xiaobo, Liu, Jiawen, Tang, Ying, Wen, Xintian   +5 more
openaire   +4 more sources

Identification of a natural recombinant transmissible gastroenteritis virus between Purdue and Miller clusters in ChinaEmerging of a natural recombinant TGEV in China [PDF]

Emerging Microbes and Infections, 2017
Transmissible gastroenteritis virus (TGEV) is an infective coronavirus (CoV) that causes diarrhea-related morbidity and mortality in piglets. For the first time, a natural recombination strain of a TGEV Anhui Hefei (AHHF) virus between the Purdue and the
Xin Zhang, Yunnuan Zhu, Xiangdong Zhu, Hongyan Shi, Jianfei Chen, Da Shi, Jing Yuan, Liyan Cao, Jianbo Liu, Hui Dong, Zhaoyang Jing, Jialin Zhang, Xiaobo Wang, Li Feng   +13 more
doaj   +3 more sources